Influence of the electromagnetic field (EMF) on the opioid drugs’ analgesic effect

• Autorzy: Bodera P. , Stankiewicz W. , Kieliszek J. , Sobiech J. , Krawczyk A. , Wojdas A. , Samochodzki Z.

Warianty tytułu

PL

Wpływ pola elektromagnetycznego na zdolność odczuwania bólu, przy jednoczesnym podawaniu opioidowych leków przeciwbólowych

• Języki publikacji: EN

Abstrakty

EN

There are two potential mechanisms of influence of the electromagnetic field (EMF) on pain perception, in parallel treatment using opioid analgesic drugs, which would be supposed to: influence the calcium channel, influence the opioid receptors, based e.g. on the cell membrane electromechanical phenomena.

PL

Zakłada się istnienie dwóch potencjalnych mechanizmów wpływu pola elektromagnetycznego na zdolność odczuwania bólu, przy jednoczesnym podawaniu opioidowych leków przeciwbólowych, a mianowicie wpływ na: ATP-azy błonowe i/lub kanały jonowe oraz receptory opioidowe. Promieniowanie elektromagnetyczne może oddziaływać na ich strukturę i modelować odpowiedź na podanie leku analgetycznego.

Słowa kluczowe

EN

electromagnetic field; opioid analgesic drugs; pain perception; QSAR modelin

PL

pole elektromagnetyczne; opiodowe leki przeciwbólowe; modelowanie QSAR

• Wydawca: Wydawnictwo SIGMA-NOT
• Czasopismo: Przegląd Elektrotechniczny
• Rocznik: 2010
• Tom: R. 86, nr 12
• Strony: 179--181
• Opis fizyczny: Bibliogr. 23 poz., rys., tab.

Twórcy

autor

Bodera P.

autor

Stankiewicz W.

autor

Kieliszek J.

autor

Sobiech J.

autor

Krawczyk A.

autor

Wojdas A.

autor

Samochodzki Z.

• Wojskowy Instytut Higieny i Epidemiologii,

Bibliografia

• [1] Lai H., Carino M.A., Horita A., Guy A.W. Opioid receptor subtypes that mediate the microwave-induced decreases in central cholinergic activity in the rat, Bioelectromagnetics 13 (1992), 237–246.
• [2] Drolet G., Dumont E.C., Gosselin I. et al. Role of endogenous opioid system in the regulation of the stress response, Prog Neuropsychopharmacol Biol Psychiatry 25 (2001), 729– 741.
• [3] Zubieta J.K., Smith Y.R., Bueller Y. et al. Regional mu opioid receptor regulation of sensory and affective dimensions of pain, Science 293 (2001), 311–315.
• [4] Prato F.S., Carson J.L., Ossenkopp K.P., Kavaliers M. Possibl mechanism by which extremely low frequency magnetic fields affect opioid function. FASEB J 9 (1995), 807–814.
• [5] Markov M.S. Myosin Light Chain Modification Depending on Magnetic Fields: II. Experimental Electromagnetic Biology and Medicine, 23 (2004), 125 – 140.
• [6] Cieślar G., Mrowiec J., Sieron A. et al. Change in the reactivity of thermal pain stimulation under influence of extremely low frequency magnetic field, Balneol. Pol. 36 (1994), 24–28. PRZEGLĄD ELEKTROTECHNICZNY (Electrical Review), ISSN 0033-2097, R. 86 NR 12/2010 181
• [7] Lai H., Carino M.A. Intracerebroventricular injections of mu- and delta-opiate receptor antagonists block 60-Hz magnetic fieldinduced decreases in cholinergic activity in the frontal cortex and hippocampus of the rat, Bioelectromagnetics 19 (1998), 432–437.
• [8] Mansour A., Lewis M.E., Khachaturian H. et al. Pharmacological and anatomical evidence of selective and opioid receptor binding in rat brain, Brain Res. 399 (1986), 69–79.
• [9] Sieroń A., Labus L., Nowak P. et al. Alternating extremely low frequency magnetic field increases turnover of dopamine and serotonin in rat frontal cortex, Bioelectromagnetics 25, 2004, 426–430.
• [10] Thomas A.W., Persinger M.A. Daily post-training exposure to pulsed magnetic fields that evoke morphine-like analgesia affects consequent motivation but not proficiency in maze learning in rats, Electro- and Magnetobiology 16 (1997), 33–41.
• [11] Zecca L., Mantegazza C., Margonato V. et al. Biological effects of prolonged exposure to ELF electromagnetic fields in rats: III 50 Hz electromagnetic fields, Bioelectromagnetics 19 (1998), 57–66.
• [12] Contet C., Kieffer B.L., Befort K., Mu opioid receptor: a gateway to drug addiction, Curr. Opin. Neurobiol. 14 (2004), 370–378.
• [13] Cieślar G., Mrowiec J., Sieron, A.. et al. Change in the reactivity of thermal pain stimulation under influence of extremely low frequency magnetic field, Balneol. Pol. 36 (1994), 24–28.
• [14] Lai H. Carino M.A., Intracerebroventricular injections of muand delta-opiate receptor antagonists block 60-Hz magnetic field-induced decreases in cholinergic activity in the frontal cortex and hippocampus of the rat, Bioelectromagnetics 19 (1998), 432–437.
• [15] Loyd D.R, Xioaya Wang X., Murphy A.Z. Sex Differences in - Opioid Receptor Expression in the Rat Midbrain Periaqueductal Gray Are Essential for Eliciting Sex Differences in Morphine Analgesia, J. Neurosc., 2008, 28(52):14007–14017
• [16] Sieroń A., Labus L., Nowak P. Alternating extremely low frequency magnetic field increases turnover of dopamine and serotonin in rat frontal cortex, Bioelectromagnetics 25 (2004), 426–430.
• [17] Yanlin L., Tianyue L., Fraser A.W. Effects of extremely lowfrequency electromagnetic fields on morphine-induced conditioned place preferences in rats, Neuroscience Letters 390 (2005) 72–75
• [18] Zecca L., Mantegazza C., Margonato V. et al. Biological effects of prolonged exposure to ELF electromagnetic fields in rats: III 50 Hz electromagnetic fields, Bioelectromagnetics 19 (1998), 57–66.
• [19] Gerrits M.A, Lesscher H.B., van Ree J.M., Drug dependence and the endogenous opioid system, Eur. Neuropsychopharmacol. 13 (2003), 424–434.
• [20] Oztas B., Kalkan T. Tuncel H. Influence of 50 Hz frequency sinusoidal magnetic field on the blood–brain barrier permeability of diabetic rats, Bioelectromagnetics 25 (2004), 400–402.
• [21] Crasson M., Legros J.J., Scarpa P. et al. 50 Hz magnetic field exposure influence on human performance and psychophysiological parameters: two double-blind experimental studies, Bioelectromagnetics 20 (1999), 474–486.
• [22] Graham C., M.R. Cook, H.D. Cohen, Gerkovich M.M., Dose response study of human exposure to 60 Hz electric and magnetic fields, Bioelectromagnetics 15 (1994), 447–463.
• [23] Carlezon W.A., Rohan M.L., Mague S.D. et al. Antidepressantlike effects of cranial stimulation within a low-energy magnetic field in rats, Biol. Psychiatry 57 (2005), 571–576