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Genotoksyczność wody do picia w wybranych wodociągach

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Warianty tytułu
EN
Genotoxicity of drinking water from some supply systems in Poland
Języki publikacji
PL
Abstrakty
EN
The ever increasing degradation of water sources, as well as the concomitant need of applying chemical disinfectants, has directed the attention of scientists and engineers to the problem of longterm exposure of human organisms to water pollutants with health hazard potential. Considering the specific physico-chemical properties of water, epidemiological studies or long-term experiments on animals are useless. For this reason, our knowledge of the potential mutagenicity of organic water pollutants is based primarily on-bacterial screening tests, such as the UMU test or the Ames test. The need of unifying the investi-gations into the mutagenicity of water gave a spur to DIN and ISO to attempt standardization of the two screening tests mentioned above. For the purpose of the present study, use was made of the Tube UMU test (which resembles the UMU microtest proposed by ISO) to evaluate the genotoxicity of water. The samples under test came from waterworks of choice (which use different treatment methods and different types of water intake), from the water-pipe network, and from oligocenic wells. The present study substantiates the utility of the UMU test in evaluating routinely the genotoxicity of drinking water. Significant genotoxicity levels were detected in the majority of disinfected water samples, and they were found to vary according to the type of intake. More advanced treatment trains (for example those involving carbon beds) bring about a substantial abatement of mutagenicity in drinking water. The genotoxicity ot the disinfected water samples should be attributed to a group of non-volatile pollutants.
Słowa kluczowe
Czasopismo
Rocznik
Tom
Strony
45--48
Opis fizyczny
Bibliogr. 21 poz., rys., wykr.
Twórcy
  • Zakład Higieny Komunalnej, Warszawa ul.Chocimska 24
Bibliografia
  • 1. B. N. AMES, J. McCANN, E. YAMASAKI: Methods for detecting carcinogens and mutagens with the Salmonella mammalian microsoma mutagenicity test. Mutation Research, 1975, 31, pp. 347-356.
  • 2. H. CZECZOT, I. RAHDEN-STAROŃ: Wybrane krótkoterminowe testy bakteryjne i na organizmach eukaryotycznych, stosowane do oceny genotoksyczności środowiskowych zanieczyszczeń chemicznych. Roczniki PZH, 1997, 48, ss. 317-336.
  • 3. M. FIELDRING, H. HORTH: Formation of mutagens and chemicals during drinking water treatment chlorination. Wat. Supply, 1986, 4, pp. 103-126.
  • 4. R. FORSTER, I. WILSON: The application of mutagenicity testing to drinking water. Journal Inst. Wat. Eng. Scient., 1981, 35, pp. 259-274.
  • 5. IARC Monograph of the evaluation of carcinogenic risks to humans. Chlorinated drinking water; chlorination by-products; some other halogenated compounds; cobalt and cobalt compounds. 1991, Vol. 52.
  • 6. D. P. JOSEPHY, P. GRUZ, T. NOIIMI: Recent advances in the construction of bacterial genotoxicity assays. Mutation Research, 1997, 386, pp. 1-23.
  • 7. T. KADA, M. MORIJA, Y. SHIRASU: Screening of pesticides of DNA interactions by REC-assay and mutagenic testing and frameshifl mutarens detected. Mutation Research, 26, pp. 243-247.
  • 8. D. MARON, B. N. AMES: Revised methods for the Salmonella mutagenicity test. Mutation Research, 1983, pp. 173-212.
  • 9. J. R. MEIER: Genotoxic activity of organic chemicals in drinking water. Mutation Research, 1988, 196, pp. 211-245.
  • 10. S. MONARCA, R. PASQUINI, P. ARCALENI: Detection of mutagens in unconcetrarted and concentrated drinking water supplies before and after treatment using a microscale fluctuation test. Chentosphere, 1985, pp. 1069-1080.
  • 11. Y. ODA, S. NAKAMURA, I. OKI, T. KATO, H. SHINAGAWA: Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens. Mutation Research, 1985, 147, pp. 219-229.
  • 12. T. PODSIADŁY: Genotoksyczność organicznych zanieczyszczeń wody pitnej. Informacja INSTAL, 1999, 5, ss. 23-25.
  • 13. T. PODSIADŁY: Genotoksyczność wody pitnej - perspektywy skri- ningu bakteryjnego. Mat. konf. "Zagadnienia medycyny środowiskowej”, PZH, Warszawa 1997.
  • 14. T. PODSIADŁY, A. KROGULSKI, M. BORKOWSKA, A. STRUSIŃSKI: Zastosowanie testu UMU w badaniach genotoksyczności zanieczy¬zczeń wody. Mat. konf. „Monitoring środowiska", 1998, ss. 591-602.
  • 15. P. QUILLARDET, M. HOFNUNG: The SOS chromotest, a colorimetric bacterial assay for genotoxins: procedures. Mutation Research, 1985, 147, pp. 65-78.
  • 16. P. QUILLARDET, M. HOFNUNG: The SOS chromotest; a review. Mutation Research, 1993, 297, pp. 235-279.
  • 17. P. QUILLARDET, C. BELLA COMBE, M. HOFNUNG :The SOS chromotest, a colorimetric assays for genotoxins: validation study with 83 compounds. Mutation Research, 1985, 147, pp. 79-95.
  • 18. J. TUOMISTO, T. VARTIANINEN: Genotoxicity of drinking waters. Complex mixtures and cancer risk. 1990, pp. 307-313.
  • 19. W. WEN-ZONG, W. KUNG-FU, J. STEWART. T. ONG: Validation of the SOS/Umu test with mutagenic mixtures. Mutation Research, 1986. 175, pp. 139-144.
  • 20. A. P. WHITE, J. B. RASSMUSSEN, C. BLAISE: A semi-automated microplate version of the SOS chromotest for the analysis of complex environmental extracts. Mutation Research, 1996, 360, pp. 51-74.
  • 21. WHO: IPCS, summary report on the evaluation of short-term tests for carcinogens (collaborative study on in vivo tests). Environmental Health Criteria, 1990, 109.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPO2-0005-0039
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