Mathematical model for biological cell deformation in a cylindrical pore

• Autorzy: Szwast M. , Suchecka T. , Piątkiewicz W.
• Języki publikacji: EN

Abstrakty

EN

Some studies show that cells are able to penetrate through pores that are smaller than cell size. It concerns especially Red Blood Cells but it also may concern different types of biological cells. Such penetration of small pores is a very significant problem in the filtration process, for example in micro or ultrafiltration. Deformability of cells allows them to go through the porous membrane and contaminate permeate. This paper shows how cells can penetrate small cylindrical holes and tries to assess mechanical stress in a cell during this process. A new mathematical approach to this phenomenon was presented, based on assumptions that were made during the microscopic observation of Red Blood Cell aspiration into a small capillary. The computational model concerns Red Blood Cell geometry. The mathematical model allows to obtain geometrical relation as well as mechanical stress relations.

Słowa kluczowe

EN

cell deformation; red blood cell; cell stamina

PL

deformacja komórek; czerwone krwinki

• Wydawca: Komitet Inżynierii Chemicznej i Procesowej Polskiej Akademii Nauk
• Czasopismo: Chemical and Process Engineering
• Rocznik: 2012
• Tom: Vol. 33, nr 3
• Strony: 385--396
• Opis fizyczny: Bibliogr. 14 poz., rys., wykr.

Twórcy

autor

Szwast M.

autor

Suchecka T.

autor

Piątkiewicz W.

• Warsaw University of Technology, Department of Chemical and Process Engineering, Warynskiego 1, 00-645 Warsaw, Poland

Bibliografia

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