Polish Artificial Heart - new coatings, technology, diagnostics

• Autorzy: Sarna J. , Kustosz R. , Major R. , Lackner J. , Major B.
• Języki publikacji: EN

Abstrakty

EN

Since 1991, the Foundation for Cardiac Surgery Development in Zabrze has been implementing research on the artificial heart. In 1995, an artificial ventricle, POLVAD, was implanted to a patient, and in 1998, the prototype of a clinical controller, POLPDU-401, was created. A further development of the studies on an implantable artificial heart requires an integrated approach and an application of advanced methods of materials sciences in order to develop new materials suitable for the contact with blood, as well as to apply a multilateral biomedical diagnostics in hydrodynamic conditions. The estimation of the cell–material interaction plays an important role in the biomaterial design. An analysis of the influence of the carbon content in titanium nitride on the biological and biophysical properties of biomaterial coatings was studied. The cell-material reactions were considered in dynamic and static conditions. Three groups of materials were under examinations – titanium nitride (TiN), as well as titanium carbonitride with a low and high carbon content – of which the best properties were observed for TiN. We found a strong influence of the stoichiometry of TiN (atomic ratio of Ti/N) on the biocompatibility. A non-stoichiometric TiN could have a negative influence on the surrounding tissue.

Słowa kluczowe

EN

pulsed laser deposition; microstructure; cell adhesion

• Wydawca: Polska Akademia Nauk, Wydział IV Nauk Technicznych
• Czasopismo: Bulletin of the Polish Academy of Sciences. Technical Sciences
• Rocznik: 2010
• Tom: Vol. 58, nr 2
• Strony: 329--335
• Opis fizyczny: Bibliogr. 10 poz., rys.

Twórcy

autor

Sarna J.

autor

Kustosz R.

autor

Major R.

autor

Lackner J.

autor

Major B.

• Foundation for Cardiac Surgery Development, 345a ,Wolności St., 41-800 Zabrze, Poland,

Bibliografia

• [1] B.D. Ratner, A.S. Hoffman, F.J. Schoen, and J.E. Lemons, Biomaterials Science, Elsevier, Bridgewater, 2004.
• [2] M. Demilly, Y. Brechet, F. Bruckert, and L. Boulang’e, “Kinetics of yeast detachment from controlled stainless steel surfaces, colloids and surfaces B”, Biointerfaces 51, 71–79 (2006).
• [3] E. Decave, Y. Brechet, F. Bruckert, and B. Fourcade, “Peeling model for cell detachment D. Garrivier”, Eur. Phys. J. E 8, 79–97 (2002).
• [4] J.M.Lackner, Industrially- scaled hybrid Pulsed Laser Deposition at Room Temperature, Orekop, Kraków, 2005.
• [5] J.A. Thornton, “Influence of apparatus geometry and deposition conditions on the structure and topography of thick sputtered coatings”, J. Vac. Sci. Technol. 11 (4), 666–670 (1974).
• [6] WinSAM Vario I to III, and SAM 2000, KSI, Kraemer Scientific Instruments, Lerchenweg, Herborn, 2000.
• [7] J. Krautkraemer and H. Krautkraemer, Ultrasonic Testing, Springer Verlag, Berlin, 1986.
• [8] A. Briggs, Acoustic Microscopy, Oxford University Press, Oxford, 1992.
• [9] Evolutin I-III, Sam Tec GmbH, [e-mail].
• [10] R. Major, F. Bruckert, J.M. Lackner, W. Waldhauser, M. Pietrzyk, and B. Major, “Kinetics of eukaryote cells adhesion under shear flow detachment on the PLD deposited surfaces”, Bull. Pol. Ac.: Tech. 56 (3), 223–228 (2008).