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Tytuł artykułu

Graph reduction and its application to DNA sequence assembly

Wybrane pełne teksty z tego czasopisma
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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The results presented here are twofold. First, a heuristic algorithm is proposed which, through removing some unnecessary arcs from a digraph, tends to reduce it into an ad joint and thus simplifies the search for a Hamiltonian cycle. Second, a heuristic algorithm for DNA sequence assembly is proposed, which uses a graph model of the problem instance, and incorporates two independent procedures of reducing the set of arcs - one of them being the former algorithm. Finally, results of tests of the assembly algorithm on parts of chromosome arm 2R of Drosophila melanogaster are presented.
Rocznik
Strony
65--70
Opis fizyczny
bibliogr. 14 poz., rys., tab.
Twórcy
autor
Bibliografia
  • [1] C. Berge, Graphs and Hypergraphs, North-Holland Publishing Company, London, 1973.
  • [2] J. Blazewicz, A. Hertz, D. Kobler, and D. de Werra, "On some properties of DNA graphs", Discrete Applied Mathematics 98, 1-19 (1999).
  • [3] G. Chartrand and L. Lesniak, Graphs and Digraphs, Wadsworth & Brooks/Cole, Pacific Grove, 1986.
  • [4] M.S. Waterman, Introduction to Computational Biology. Maps, Sequences and Genomes, Chapman & Hall, London, 1995.
  • [5] J. Setubal and J. Meidanis, Introduction to Computational Molecular Biology, PWS Publishing Company, Boston, 1997.
  • [6] P.A. Pevzner, Computational Molecular Biology: an Algorithmic Approach, MIT Press, Cambridge, 2000.
  • [7] W. Bains and G.c. Smith, "A novel method for nucleic acid sequence determination", J. of Theoretical Biology 135,303-307 (1988).
  • [8] Yu.P. Lysov, V.L. Florentiev, A.A. Khorlin, K.R. Khrapko, VV Shik, and A.D. Mirzabekov, "Determination of the nucleotide sequence of DNA using hybridization with oligonucleotides. A new method", Dokl. Akad. Nauk SSSR 303, 1508-1511 (1988).
  • [9] A.M. Frieze, EP. Preparata, and E. Upfal, "Optimal reconstruction of a sequence from its probes", J. of Computational Biology 6, 361-368 (1999).
  • [10] J. Blazewicz, P. Formanowicz, M. Kasprzak, W.T. Markiewicz, and J. Weglarz, "DNA sequencing with positive and negative errors", J. of Computational Biology 6, 113-123 (1999).
  • [11] J. Blazewicz, P. Formanowicz, E Guinand, and M. Kasprzak, "A heuristic managing errors for DNA sequencing", Bioinformatics 18, 652-660 (2002).
  • [12] M.R. Garey and D.S. Johnson, Computers and Intractability. A Guide to the Theory of NP-Completeness, W.H. Freeman and Company, San Francisco, 1979.
  • [13] J. Blazewicz, M. Figlerowicz, P. Formanowicz, M. Kasprzak, B. Nowierski, R. Styszynski, L. Szajkowski, P. Widera, and M. Wiktorczyk, "Assembling the SARS-CoV genome - new method based on graph theoretical approach", Acta Biochimica Polonica 51, 983-993 (2004).
  • [14] S.B. Needleman and C.D. Wunsch, "A general method applicable to the search for similarities in the amino acid sequence of two proteins",J. Molecular Biology 48, 443--453 (1970).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPG5-0031-0010
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