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Development of "virtual patient" model for simulation of solute and fluid transport during dialysis

Wybrane pełne teksty z tego czasopisma
Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Optimization of dialysis needs methods for quantitative assessment of fluid and solutes transport in body compartments and solute and fluid exchange between body and dialysate. A mathematical model describing the dynamics of these quantities during dialysis is presented. This model is first and foremost based on the existing models, but also includes some new solutions. All parts were combined and extended by the detailed descriptions of selected aspects. The "virtual patient" model was applied to simulate and test different methods of treatment and their influence on the condition of the patient. The purpose of this model is to serve as a decision support system for selection of "optimal" treatment options for particular patient.
Słowa kluczowe
Rocznik
Strony
283--292
Opis fizyczny
Bibliogr. 22 poz., 12 rys.
Twórcy
autor
autor
  • Institute of Biocybemetics and Biomedical Engineering, Polish Academy of Science 4 Ks. Trojdena Str., 02-109 Warsaw, Poland., magda@ibib.waw.pl
Bibliografia
  • [1] J.T. Daugirdas, P.G. Blake, and S. Todd, Handbook of Dialysis, Lippincot, Williams and Wilkins, 2001.
  • [2] M. Ursino and M. Innocenti, “Modeling arterial hypotension during hemodialysis”, Artif. Organs 21(8), 873–890 (1997).
  • [3] L. Coli, M. Ursino, A. De Pascalis, C. Brighenti, V. Dalmastri, G. La Manna, E. Isola, G. Cianciolo, D. Patrono, P. Boni, and M. Gałach and A. Wery´nski S. Stefoni, “Evaluation of intradialytic solute and fluid kinetics. Setting up a predictive mathematical model”, Blood Purif. 18(1), 37–49 (2000).
  • [4] B. Rippe, and L. Levin, “Computer simulations of ultrafiltration profiles for an icodextrin-based peritoneal fluid in CAPD”, Kidney Int. 57(6), 2546–2556 (2000).
  • [5] M.C.K. Khoo, Physiological Control Systems; Analysis, Simulation, and Estimation, New York, IEEE Press, 2000.
  • [6] M. Galach, A. Ciechanowska, S. Sabalinska, J. Waniewski, J. Wojcicki, and A. Werynski, “Impact of convective transport on dialyzer clearance”, J. Artif. Organs 6(1), 42–48 (2003).
  • [7] M. Galach and A. Werynski, “Mathematical modeling of renal replacement therapies”, Biocybernetics and Biomedical Engineering 24(4), 3–18 (2004).
  • [8] A.C. Guyton, Textbook of Medical Physiology, W.B. Saunders Company, 1981.
  • [9] W. Grzeszczak, “Diabetes mellitus – serious nefrological problem in XXI century”, Progresses of Medical Sciences XIV(1– 2), (2003), (in Polish).
  • [10] V.B. Mountcastle, Medical Physilogy, St. Louis, C.V. Mosby, 1974.
  • [11] M. Darowski, T. Orłowski, A. Wery´nski, and J.M. Wójcicki, “Artificial organs”, Biocybernetics and Biomedical Engineering 2000 3, 523 (2001), (in Polish).
  • [12] A. Werynski, “Evaluation of the impact of ultrafiltration on dialyzer clearance”, Artif. Organs 3(2), 140–142 (1979).
  • [13] B. Rippe, B.I. Rosengren, and D. Venturoli, “The peritoneal microcirculation in peritoneal dialysis”, Microcirculation 8(5), 303–320 (2001).
  • [14] D. Venturoli and B. Rippe, “Transport asymmetry in peritoneal dialysis: application of a serial heteroporous peritoneal membrane model”, Am. J. Physiol. Renal Physiol. 280(4), F599–606 (2001).
  • [15] M.F. Flessner, “The transport barrier in intraperitoneal therapy”, Am. J. Physiol. Renal Physiol. 288(3), F433–442 (2005).
  • [16] D.G. Struijk, G.C. Koomen, R.T. Krediet, and L. Arisz, “Indirect measurement of lymphatic absorption in CAPD patients is not influenced by trapping”, Kidney Int. 41(6), 1668–1675 (1992).
  • [17] S.B. Jenkins and M.E.Wilkie, “An exploratory study of a novel peritoneal combination dialysate (1.36% glucose/7.5% icodextrin), demonstrating improved ultrafiltration compared to either component studied alone”, Perit. Dial. Int. 23(5), 475–480 (2003).
  • [18] J.T. Daugirdas, T.S. Ing, V.C. Gandhi, J.E. Hano, W.T. Chen, and L. Yuan, “Kinetics of peritoneal fluid absorption in patients with chronic renal failure”, J. Lab. Clin. Med. 95(3), 351–361 (1980).
  • [19] J. Waniewski, O. Heimburger, A. Werynski, and B. Lindholm, “Simple models for fluid transport during peritoneal dialysis”, Int. J. Artif. Organs 19(8), 455–466 (1996).
  • [20] M. Flessner, “Effective lymphatic absorption rate is not a useful or accurate term to use in the physiology of peritoneal dialysis”, Perit. Dial. Int. 24(4), 313–316, discussion 316–317 (2004).
  • [21] R.T. Krediet, “The effective lymphatic absorption rate is an accurate and useful concept in the physiology of peritoneal dialysis”, Perit. Dial. Int. 24(4), 309–313, discussion 316–307 (2004).
  • [22] I. Uhlenbush-Korwer, E. Bonnie-Schorn, A. Grassmann, and J. Vienken, Understanding Membranes and Dialysers, Lengerich: Pabst Science Publishers, 2004.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPG5-0006-0010
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