New gradient coatings on TiN and TiCN basis for biomedical application to blood contact

• Autorzy: Major B. , Major R. , Bruckert F. , Lackner J.M. , Ebner R. , Kustosz R. , Lacki P.
• Języki publikacji: EN

Abstrakty

EN

Adhesion of blood cells and its activation to material surface used as implants is a problem of crucial importance. Structure parameters influence essentially the interaction of biomedical materials with a human connective tissue. The work is focused on TiN and TiCN thin coatings produced on titanium substrate by application of different methods i.e. pulsed laser deposition (PLD), magnetron sputtering, and hybrid PLD, at room temperature. Biophysical tests of the kinetics of shear flow-induced cell detachment have been carried out. Model eucariotic cells easy to manipulate using technics of molecular biology have been used in experiments. Fluorescence patterns obtained after the performed test at kinetics condition tests have been used to establish kinetics curves. A microstructure examination by application of XRD and transmission electron microscopy have been performed. The work is realized in cooperation with the Foundation of Cardiac Surgery Development in the frame-work of partially implanted prosthesis of the artificial heart project.

Słowa kluczowe

EN

biomedical coatings; cell adhesion; microstructure

• Wydawca: Politechnika Gdańska
• Czasopismo: Advances in Materials Science
• Rocznik: 2007
• Tom: Vol. 7, nr 3(13)
• Strony: 63--70
• Opis fizyczny: Bibliogr. 13 poz., rys., tab.

Twórcy

autor

Major B.

autor

Major R.

autor

Bruckert F.

autor

Lackner J.M.

autor

Ebner R.

autor

Kustosz R.

autor

Lacki P.

• Institute of Metallurgy and Materials Science Pol. Acad. of Sci., Cracow, Poland

Bibliografia

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