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Numerical modeling of biological tissue heating : admissible thermal dose

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EN
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EN
The cylindrical domain of skin tissue subjected to an external heat flux is considered (shape of domain is determined by form of function describing Neumann boundary condition on external surface of the system). The first version of numerical simulations concerns the heterogeneous multi-layered skin tissue domain (epidermis, dermis, subcutaneous region). The thermophysical parameters of successive layers are assumed to be different, but constant. The second version of computations concerns the homogeneous domain, but the mean values of the thermophysical parameters are temperature-dependent (non-linear task). Knowledge of the spatial, time-dependent temperature field allows one to determine the so-called thermal dose and also the degree of tissue destruction. The algorithm presented can be useful in medical practice, among others, at the stage of the hyperthermia therapy scheme.
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Bibliografia
  • [1] Torvi D.A., Dale J.D., A finite element model of skin subjected to a flash fire, Journal of Biomechanical Engineering 1994, 116, 250-255.
  • [2] Mochnacki B., Dziewonski M., Poteralska J., Thermal effects in domain of tissue subjected to an external heat source, Computational Modeling and Advanced Simulations, CMAS 2009, Bratislava 2009, 1, 10.
  • [3] Stańczyk M., Telega J.J., Modelling of heat transfer in biomechanics - a review, Part I: Soft tissues, Acta of Bioengineering and Biomechanics 2002, 4, 1, 31-61.
  • [4] Majchrzak E., Modelowanie i analiza zjawisk termicznych, [in:] Mechanika Techniczna, Biomechanika, Tom XII, cz. IV, IPPT PAN, 2011, 223-362.
  • [5] Majchrzak E., Jasiński M., Sensitivity analysis of burn integrals, Computer Assisted Mechanics and Engineering Sciences 2004, 11, 2/3, 125-136.
  • [6] Majchrzak E., Mochnacki B., Analysis of bio-heat transfer in the system of blood vessel biological tissue, Kluwer Academic Publishers 2001, 201-211.
  • [7] Majchrzak E., Mochnacki B., Jasiński M., Numerical modelling of bioheat transfer in multilayer skin tissue domain subjected to a flash fire, Computational Fluid and Solid Mechanics, Elsevier 2003, Vol. II, 1766-1770.
  • [8] Ng E. Y-K., Chua L.T., Prediction of skin burn injury, Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 2002, 216, 171-183.
  • [9] Xu F., Lu T.J., Seffen K.A., Biothermomechanics of skin tissues, Journal of the Mechanics and Physics of Solids 2008, 58, 1852-1884.
  • [10] Mochnacki B, Suchy J.S., Numerical methods in computations of foundry processes, PFTA, Cracow 1995.
  • [11] Mochnacki B., Ciesielski M., Modelowanie nagrzewania tkanki skórnej, dopuszczalna dawka termiczna, II Kongres Mechaniki Polskiej, Poznań 2011, 1-14.
  • [12] Abraham J.P., Sparrow E.M., A thermal-ablation bioheat model including liquid-to vapour phase change, pressure- and necrosis-dependent perfusion, and moisture-dependent properties, International Journal of Heat and Mass Transfer 2007, 50, 2537-2544.
  • [13] Majchrzak E., Mochnacki B., Metody numeryczne. Podstawy teoretyczne, aspekty praktyczne, algorytmy, Wydawnictwa Politechniki Śląskiej, Gliwice 2004.
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Bibliografia
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bwmeta1.element.baztech-article-BPC6-0015-0002
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