PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Powiadomienia systemowe
  • Sesja wygasła!
  • Sesja wygasła!
  • Sesja wygasła!
Tytuł artykułu

Evalution of the propiertes biodegradable polymeric materials based on polysuccinate resin and methacrylated digosuccinates

Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Biodegradable bone cements are promising biomaterials for bone surgery. Liquid compositions are crosslinked in situ and provide temporary structural support to bone tissue, then degrade to biocompatible products at slow rate, adapted to bone healing. In this study selected properties of new biodegradable polymeric materials based on poly(3-allyloxy-l,2-propylene succinate) (PSAGE), methacrylated oligo(3-allyloxy-l,2- propylene succinate) (MOSAGE) and small quantity of low-viscous monomers: methacrylic anhydride (MAAH) and methyl methacrylate (MMA) were investigated. Chemical structure of obtained oligoesters was confirmed by 'H NMR and ESI-MS analysis. Mechanical properties of crosslinked material were characterized by compressive strength, compressive modulus and Shore hardness. Hydrolytic degradation of the cured compositions was carried out in phosphate buffer solution (PBS, pH=7.41) at 37°C. The process followed by determination of weight loss appeared to be relatively fast (30-50 wt % after 2 months).
Rocznik
Strony
51--56
Opis fizyczny
Bibliogr. 16 poz., rys., tab.
Twórcy
autor
  • 'Silesian University of Technology, Department of Physical Chemistry and Technology of Polymers, M. Strzody 9, 44-100 Gliwice, Poland, Jan.Lukaszczyk@poIsl.pl
Bibliografia
  • [1] Domb A.J., Manor N., Elmalak O., Biomaterials 1996, 17, 411.
  • [2] Peter S.J., Suggs L.J., Yaszemski M.J., Engel P.S., Mikos A.G., J. Biomater. Sci. Polymer Edn, 1999,10, 363.
  • [3] Timmer M.D., Ambrose C.G., Mikos A.G., J. Biomed. Mater. Res. 66A, 2003, 66, 811.
  • [4] Burkoth A.K., Burdick J.A., Anseth K.S., J. Biomed. Mater. Res., 2000, 51, 352.
  • [5] Young J.S., Gonzales K.D., Anseth K.S., Biomaterials, 2000, 21, 1181.
  • [6] Watkins A.W., Anseth K.S., J. Biomater. Sci. Polymer Edn., 2003, 14, 267.
  • [7] Storey R.F., Warren S.C., Allison C.J., Puckett A.D., Polymer, 1997, 38, 6295.
  • [8] Helminen A.O., Korhonen H., Seppala J.V., J. Appl. Polym. Sci., 2002, 86, 3616.
  • [9] Davis K.A., Burdick J.A., Anseth K.S., Biomaterials, 2003, 24, 2485.
  • [10] Galibert P., Deramond H., Rosat P., Le Gars D., Neurochirurgie, 1987, 3, 166.
  • [11] Lieberman I.H., Togawa D., Kayanja M.M., Spine J., 2005, 5, 305S.
  • [12] Heini P.F., Berlemann U., Eur. Spine J., 2001, 10, 205.
  • [13] Łukaszczyk J., Jaszcz K., React. Fund. Polym., 2000, 43, 25.
  • [14] Ramakrishna S., Mayer J., Wintermantel E., Leong Kam W., Composites Sci. Techn., 2001, 61, 1189.
  • [15] Yaszemski M.J., Payne R.G., Hayes W.C., Langer R., Mikos A.G., Biomaterials, 1996, 17, 175.
  • [16] E. Reichmanis, M. Jaffe in: Applied Polymer Science 21“ century, C.D. Craver, C.E. Jr. Carraher, Ed.; Elsevier Science, Amsterdam, 2000, 591.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPC2-0006-0008
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.