Processing of biodegradable linear polyurethane for different medical applications

• Autorzy: Laska J. , Błażewicz S.
• Języki publikacji: EN

Abstrakty

EN

Polyurethanes are frequently used as biomaterials due to their biocompatibility and fatigue resistance. Their properties can be easily differentiated by changing the length or amount of the hard and soft segments. Linear elastomeric and biodegradable polyurethane prepared from aliphatic diisocyanate, poly(s-caprolactone) diol, and biologically active isosorbide diol as a chain extender was processed into membranes and elastic foams. Smooth and porous highly flexible membranes were obtained by combination of solvent-nonsolvent phase-inverse process and salt leaching. The polyurethane was also blended with polylactide in purpose to change mechanical properties and resorption time of the material. The obtained materials are presently examined as potential scaffolds for skin and bone tissue engineering and for nerve guidance channels.

Słowa kluczowe

EN

polyurethanes; biodegradable materials; processing; medical applications

PL

poliuretany; biodegradowalne materiały; przetwórstwo; zastosowania medyczne

• Wydawca: Centrum Materiałów Polimerowych i Węglowych PAN
• Czasopismo: Polish Journal of Applied Chemistry
• Rocznik: 2009
• Tom: Vol. 53, nr 1
• Strony: 43--49
• Opis fizyczny: Bibliogr. 10 poz., rys., tab.

Twórcy

autor

Laska J.

autor

Błażewicz S.

• AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Biomaterials, Mickiewicza Av. 30, 30-059 Krakow, Poland,

Bibliografia

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• [7] Wright, J.I., Medical Device & Diagnostic Industry Archive, March 2006 (online ed.).
• [8] Hench L.L. (Ed.) and Jones J.R. (Ed.), Biomaterials, artificial organs and tissue engineering, Woodhead Publ. Ltd & CRC Press LLC, 2005, p. 101.
• [9] Borozino, J. D., Biomedical Engineering Handbook, Chapter 134, Boca Raton, CRC Press.
• [10] Goma, K., Gogolewski, S., J. Biomed. Mat. Res. Part A, 2006, 79A, 128. Hench, L.L. Polak, J.M., Science, 2002, 295, 1014.