Mechanical, biological, and microstructural properties of biodegradable models of polymeric stents made of PLLA and alginate fibers

• Autorzy: Bartkowiak-Jowsa M. , Będziński R. , Szaraniec B. , Chłopek J.
• Języki publikacji: EN

Abstrakty

EN

Due to lack of effective methods for preventing the complications associated with stent implantation, the search for new solutions is conducted, including those based on the use of biodegradable polymers. Such materials could allow us to develop a temporary implant that would ensure flow in the vessel until its regeneration, while minimising the negative effects connected with long--erm implant–tissue interaction. In this study, models in the form of biodegradable stents of different materials and geometry were prepared. Due to the fact that one of the basic requirements imposed on vascular stents is the ability to resist radial loads caused by the surrounding tissue, the maximum radial forces causing destruction of prepared models were investigated. The results were compared with the values obtained for commercially used metallic implants. Models were also incubated in Eagle's medium enriched with albumin in order to assess potential adhesion capacity of proteins on their surface. Scanning electron microscope enabled monitoring of microstructural changes during incubation. The results obtained were used to evaluate the ability to obtain a functional, biodegradable vascular stent.

Słowa kluczowe

EN

power; biodegradable stent; radial strength; mechanical properties; biological properties; polymer structure

PL

moc; biodegradacja stentu; siła promieniowa; właściwości mechaniczne; właściwości biologiczne; struktura polimerowa

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 2011
• Tom: Vol. 13, no. 4
• Strony: 21--28
• Opis fizyczny: Bibliogr. 31 poz., rys., tab.

Twórcy

autor

Bartkowiak-Jowsa M.

autor

Będziński R.

autor

Szaraniec B.

autor

Chłopek J.

• Wrocław University of Technology, Division of Biomedical Engineering and Biomechanics,

Bibliografia

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