Anisotropy of demineralized bone matrix under compressive load

• Autorzy: Trębacz H. , Zdunek A.
• Języki publikacji: EN

Abstrakty

EN

Two groups of cubic specimens from diaphysis of bovine femur, intact and completely demineralized, were axially compressed. One half of the samples from each group were loaded along the axis of the femur (L) and the other - perpendicularly (T). Intact samples were characterized in terms of elastic modulus; for demineralized samples secant modulus of elasticity was calculated. During compression an acoustic emission (AE) signal was recorded and AE events and energy were analyzed. Samples of intact bone did not reveal any anisotropy under compression at the stress of 80 MPa. However, AE signal indicated an initiation of failure in samples loaded in T direction. Demineralized samples were anisotropic under compression. Both secant modulus of elasticity and AE parameters were significantly higher in T direction than in L direction, which is attributed to shifting and separation of lamellae of collagen fibrils and lamellae in bone matrix.

Słowa kluczowe

EN

acoustic emission; anisotropy; bone matrix; compression; cortical bone

PL

emisja akustyczna; anizotropia; matryca kości; kompresja; kość korowa

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 2011
• Tom: Vol. 13, no. 1
• Strony: 71--76
• Opis fizyczny: Bibliogr. 22 poz., rys., tab.

Twórcy

autor

Trębacz H.

autor

Zdunek A.

• Department of Biophysics, Medical University of Lublin,

Bibliografia

• [1] ALANDER P., LASSILA V.J., TEZVERGIL A., VALLITTU P.K., Acoustic emission analysis of fiber-reinforced composite in flexural testing, Dental Materials, 2004, 20, 305–312.
• [2] BOWMAN S.M., ZEIND J., GIBSON L.J., HAYES W.C., McMAHON T.A., The tensile behavior of demineralized bovine cortical bone, J. Biomechanics, 1996, 29(11), 1497–1501.
• [3] BROWNE M., JEFFERS J.R.T., SAFFARI N., Nondestructive evaluation of bone cement and bone cement/metal interface failure, J. Biomed. Mater. Res. Part B: Appl. Biomater., 2010, 92B, 420–429.
• [4] BURR D.B., SCHAFFLER M.B., FREDERICKSON R.G., Composition of the cement line and its possible mechanical role as a local interface in human compact bone, J. Biomech., 1988, 21(11), 939–945.
• [5] CATANESE J. 3rd, IVERSON E.P., KEAVENY T.M., Heterogeneity of the mechanical properties of demineralized bone, J. Biomech., 1999, 32(12), 1365–1369.
• [6] CURREY J.D., Physical characteristics affecting the tensile failure properties of compact bone, J. Biomech., 1990, 23(8), 837–844.
• [7] FISCHER R.A., ARMS S.W., POPE M.H., SELIGSON D., Analysis of the effect of using two different strain rates on the acoustic emission in bone, J. Biomech., 1986, 19(2), 119–127.
• [8] GLOWACKI J., MIZUNO S., Collagen scaffolds for tissue engineering, Biopolymers, 2008, 89(5), 338–344.
• [9] HANSEN U., ZIOUPOS P., SIMPSON R., CURREY J.D., HYND D., The effect of strain rate on the mechanical properties of human cortical bone, J. Biomech. Eng., 2008, 130(1), 011011.
• [10] HASEGAWA K., TURNER C.H., BURR B., Contribution of collagen and mineral to the elastic anisotropy of bone, Calcif. Tissue Int., 1994, 55, 381–386.
• [11] NYMAN J.S., LENG H., NEIL DONG X., WANG X., Differences in the mechanical behavior of cortical bone between compression and tension when subjected to progressive loading, J. Mech. Behav. Biomed. Mater., 2009, 2(6), 613–619.
• [12] SASAKI N., ENYO A., Viscoelastic properties of bone as a function of water content, J. Biomech., 1995, 28(7), 809–815.
• [13] SASAKI N., NOZOE T., NISHIHARA R., FUKUI A., Effect of mineral dissolution from bone specimens on viscoelastic properties of cortical bone, J. Biomech., 2008, 41(16), 3511–3514.
• [14] SUMMITT M.C., REISINGER K.D., Characterization of the mechanical properties of demineralized bone, J. Biomed. Mater. Res. A, 2003, 67(3), 742–750.
• [15] TAI K., QI H.J., ORTIZ C., Effect of mineral content on the nanoindentation properties and nanoscale deformation mechanisms of bovine tibial cortical bone, J. Mater. Sci. Mater. Med., 2005, 16, 947–959.
• [16] TAKANO Y., TURNER C.H., BURR D.B., Mineral anisotropy In mineralized tissues is similar among species and mineral growth occurs independently of collagen orientation in rats: results from acoustic velocity measurements, J. Bone Miner. Res., 1996, 11(9), 1292–1301.
• [17] TRĘBACZ H., GAWDA H., Velocity of ultrasonic waves In cortical bone after gradual demineralization of bone tissue, Arch. Acoustics, 2005, 30 (4), 267–270.
• [18] TRĘBACZ H., ZDUNEK A., Three-point bending and acoustic emission study of adult rat femora after immobilization and free remobilization, J. Biomech., 2006, 39, 237–245.
• [19] WAGNER H.D., WEINER S., On the relationship between the microstructure of bone and its mechanical stiffness, J. Biomech., 1993, 25(11), 1311–1320.
• [20] YAN J., DAGA A., KUMAR R., MECHOLSKY J.J., Fracture toughness and work of fracture of hydrated, dehydrated, and ashed bovine bone, J. Biomech., 2008, 41, 1929–1936.
• [21] YENI Y.N., SCHAFFLER M.B., GIBSON G., FYHRIE D., Prestress due to dimensional changes caused by demineralization: a potential mechanism for microcraking in bone, Ann. Biomed. Eng., 2002, 30, 217–225.
• [22] ZDUNEK A., BEDNARCZYK J., Effect of mannitol treatment on ultrasound emission during texture profile analysis of potato and apple tissue, J. Texture Studies, 2006, 37, 339–359.