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The serious problem of angioplasty is restenosis, which relates to approx. 15–30% of all the patients subjected to the procedure. The present research was inspired by an attempt to explain this phenomenon and to analyse its causes. Two coronary arteries coming from the patients after stent implantation were subjected to analysis using light and electron microscopy. As a result of expansion of the stent and pressing the implant metallic structure into the artery wall, it comes to breaking the endothelium continuity, uncovering the structures of the intercellular matrix and the internal membrane and, consequently, to creation of a thrombus in the damaged area. As a result of the tissue response, the extracellular matrix is created and neointime formed.
Czasopismo
Rocznik
Tom
Strony
55--60
Opis fizyczny
Bibliogr. 17 poz., rys.
Twórcy
autor
autor
autor
- Institute of Materials Science and Applied Mechanics, Wrocław University of Technology, dominika.grygier@pwr.wroc.pl
Bibliografia
- [1] ŁANDA K., PLISKO R., WCISŁO J. et al., Comparison of clinical and costly effectiveness of a rapamycine releasing stent with invasive cardiology methods commonly used in Poland in treatment of heart ischemic disease, HTA Consulting, Kraków, 2002.
- [2] GIECA L., Heart ischemic disease, Wydawnictwo Lekarskie PZWL, Warsaw, 1996.
- [3] GRUNTZIG A.R., SENNING A., SIEGENTHALER W.E., Nonoperative dilatation of coronary artery stenosis: peracutaneous transluminal coronary angioplasty, N. Engl. J. Med., 1979, 301, 61–68.
- [4] KUBICA J., MARSICO F., SUKIENNIK A. et al., Intravessel stents. Angiographic and ultrasonographic assessment after implantation and at distant examination, Kardiologia Polska, 1996, 45, 502–507.
- [5] FISCHMAN D.L., LEON M.B., BAIM D.S. et al., A randomized comparison of coronary stent placement and balloon angioplasty in the treatment of coronary artery disease, N. Engl. J. Med., 1994, 331, 496–501.
- [6] NAKATANI M., TAKEYAMA Y., SHIBATA M. et al., Mechanisms of restenosis after coronary intervention. Difference between plain old balloon angioplasty and stenting, Cardiovascular Pathology, 2003, 12, 40–48.
- [7] DĄBROWSKI M., DĘBSKI A., NORWA-OTTO B. et al., Five-year clinical observation of patients after successful percutaneous transluminal coronary angioplasty (PTCA), Nowa Medycyna, 1997, 14, 31–37.
- [8] GIL R., KUBICA J., CADILLAC examination – summary, Kardiologia Inwazyjna, 2001, 2(11), 15–16.
- [9] SERRUYS P.W., DE JAEGERE P., KIEMENEIJ F. et al., A comparison of balloon-expandable stent implantation with balloon angioplasty in patients with coronary artery disease, N. Engl. J. Med., 1994, 331, 489–495.
- [10] SERRUYS P., KUTRYK M., Handbook of coronary stents, Martin Dunitz Ltd, 1998.
- [11] WELT F.G.P., ROGERS C., Inflammation and restenosis in the stent era, Arterioscler. Thromb. Vasc. Biol., 2002, 22, 1769–1776.
- [12] FARB A., WEBER D.K., KOLODGIE F.D. et al., Morphological predictors of restenosis after coronary stenting in humans, Circulation, 2002, 105, 2974–2980.
- [13] KEARNEY M., PIECEK A., HALEY L. et al., Histopathology of in-stent restenosis in patients with peripheral artery disease, Circulation, 1997, 95, 1998–2002.
- [14] FORRESTER J.S., FISHBEIN M., HELFANT R. et al., A paradigm for restenosis based on cell biology: clues for the development of new preventive therapies, J. Am. Coll. Kardiol., 1991, 17, 758–769.
- [15] DUDKA D., RZESZUTKO Ł., Does restenosis phenomenon still limits coronary angioplasty effectiveness? Wydawnictwo Medyczne, Kraków, 2003.
- [16] BOCHENEK A., REICHER M., Human anatomy, Wydawnictwo Lekarskie PZWL, Warszawa, 1998.
- [17] BORODULIN-NADZIEJA L., Human physiology, Dexter Oficyna Wydawnicza, Wrocław, 1999.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPB9-0013-0009