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Microscopic and histological analysis of the processes occurring in the aperture and wall of a coronary vessel after stent implantation

Wybrane pełne teksty z tego czasopisma
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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The serious problem of angioplasty is restenosis, which relates to approx. 15–30% of all the patients subjected to the procedure. The present research was inspired by an attempt to explain this phenomenon and to analyse its causes. Two coronary arteries coming from the patients after stent implantation were subjected to analysis using light and electron microscopy. As a result of expansion of the stent and pressing the implant metallic structure into the artery wall, it comes to breaking the endothelium continuity, uncovering the structures of the intercellular matrix and the internal membrane and, consequently, to creation of a thrombus in the damaged area. As a result of the tissue response, the extracellular matrix is created and neointime formed.
Rocznik
Strony
55--60
Opis fizyczny
Bibliogr. 17 poz., rys.
Twórcy
autor
autor
Bibliografia
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  • [6] NAKATANI M., TAKEYAMA Y., SHIBATA M. et al., Mechanisms of restenosis after coronary intervention. Difference between plain old balloon angioplasty and stenting, Cardiovascular Pathology, 2003, 12, 40–48.
  • [7] DĄBROWSKI M., DĘBSKI A., NORWA-OTTO B. et al., Five-year clinical observation of patients after successful percutaneous transluminal coronary angioplasty (PTCA), Nowa Medycyna, 1997, 14, 31–37.
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  • [9] SERRUYS P.W., DE JAEGERE P., KIEMENEIJ F. et al., A comparison of balloon-expandable stent implantation with balloon angioplasty in patients with coronary artery disease, N. Engl. J. Med., 1994, 331, 489–495.
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  • [11] WELT F.G.P., ROGERS C., Inflammation and restenosis in the stent era, Arterioscler. Thromb. Vasc. Biol., 2002, 22, 1769–1776.
  • [12] FARB A., WEBER D.K., KOLODGIE F.D. et al., Morphological predictors of restenosis after coronary stenting in humans, Circulation, 2002, 105, 2974–2980.
  • [13] KEARNEY M., PIECEK A., HALEY L. et al., Histopathology of in-stent restenosis in patients with peripheral artery disease, Circulation, 1997, 95, 1998–2002.
  • [14] FORRESTER J.S., FISHBEIN M., HELFANT R. et al., A paradigm for restenosis based on cell biology: clues for the development of new preventive therapies, J. Am. Coll. Kardiol., 1991, 17, 758–769.
  • [15] DUDKA D., RZESZUTKO Ł., Does restenosis phenomenon still limits coronary angioplasty effectiveness? Wydawnictwo Medyczne, Kraków, 2003.
  • [16] BOCHENEK A., REICHER M., Human anatomy, Wydawnictwo Lekarskie PZWL, Warszawa, 1998.
  • [17] BORODULIN-NADZIEJA L., Human physiology, Dexter Oficyna Wydawnicza, Wrocław, 1999.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPB9-0013-0009
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