Effect of treadmill exercise on lumbar vertebrae in ovariectomized rats: anthropometrical and mechanical analyses

• Autorzy: Simoes P. A. , Zamarioli A. , Bloes P. , Mazzocato F. C. , Pereira L. H. A. , Volpon J. B. , Shimano A. C.
• Języki publikacji: EN

Abstrakty

EN

The purpose of this study was to examine the preventive effect of exercise on lumbar vertebrae in ovariectomized rats. Three-monthold female Wistar rats were divided into 3 groups: control group (A, n = 10); non-exercised ovariectomized group (B, n = 7) and exercised ovariectomized group (C, n = 7). The rats from group C were subjected to treadmill exercise (15 m/minute in the initial six weeks and 19 m/minute in the next six weeks, 1 hour/day, 4 days/week) for 12 weeks. At death, the fourth lumbar vertebrae were removed and an anthropometrical analysis by a paquimeter and a mechanical compression test by a universal test machine were performed. After 12 weeks, the ovariectomy decreased the superior–inferior vertebral height and the maximal braking load in group B compared to group A, while the exercise increased the vertebral mass in group C compared to both groups A and B ( p < 0.01) and the stiffness compared to group B. We concluded the physical activity has an important role to prevent the osteopenia in lumbar vertebrae.

Słowa kluczowe

EN

osteopenia; biomechanics; ovariectomy

PL

spine; kręgosłup; biomechanika

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 2008
• Tom: Vol. 10, nr 2
• Strony: 39--41
• Opis fizyczny: Bibliogr. 14 poz.,

Twórcy

autor

Simoes P. A.

autor

Zamarioli A.

autor

Bloes P.

autor

Mazzocato F. C.

autor

Pereira L. H. A.

autor

Volpon J. B.

autor

Shimano A. C.

• University of Săo Paulo, Faculty of Medicine of Ribeirăo Preto

Bibliografia

• [1] CANALIS E., Regulation of bone remodeling, [in:] Primer on the Metabolic Bone Disease and Disorders of Mineral Metabolism, 3rd ed., M. Favus (ed.), Philadelphia, New York, 1966, Lippincott-Raven, 29–34.
• [2] RIGGS B.L., MELTON III L.J., The worldwide problem of osteoporosis: insights afforded by epidemiology, Bone, New York, Nov. 1995, Vol. 17, No. 5(suppl.), 5055–5115.
• [3] BARENGOLTS E.I., CURRY D.J., BAPNA M.S., KUKREJA S.C., Effects of endurance exercise on bone mass and mechanical properties in intact and ovariectomized rats, J. Bone Miner. Res., Aug. 1993, Vol. 8, No. 8, 937–942,
• [4] BONNET N., BEAUPIED H., VICO L., DOLLEANS E., LAROCHE N., COURTEIX D., BENHAMOU C.L., Combined effects of exercise and propanolol on bone tissue in ovariectomized rats, J. Bone Miner. Res., Apr. 2007, Vol. 22, No. 4, 578–588.
• [5] CHEN M.M., YEH J.K., ALOIA J.F., TIERNEY J.M., SPRINTZ S., Effect of treadmill exercise on tibial cortical bone in aged female rats: a histomorphometry and dual energy X-ray absorptiometry study, Bone, New York, May–June 1994, Vol. 15, No. 3, 313–319.
• [6] GALA J., DÍAZ-CURIEL M., LA PIEDRA C., CALERO J., Shortand long-term effects of calcium and exercise on bone mineral density in ovariectomized rats, British J. Nutrition, 2001, Vol. 86, 521–527.
• [7] NOTOMI T., OKIMOTO N., OKAZAKI Y., NAKAMURA T., SUZUKI M., Tower climbing exercise started 3 months after ovariectomy recovers bone strength of the femur and lumbar vertebrae in aged osteopenic rats, J. Bone Miner. Res., Jan. 2003, Vol. 18, No. 1, 140–149.
• [8] OCARINO N.M., MARUBAYASHI U., CARDOSO T.G.S., GUIMARÃES C.V., SILVA A.E., TÔRRES R.C.S., SERAKIDES R., Physical activity in osteopenia treatment improved the mass of bones directly and indirectly submitted to mechanical impact, J. Musculoskelet. Neuronal. Interact., 2007, Vol. 7, No. 1, 84–93.
• [9] PENG Z., TUUKKANEN J., VÄÄNÄNEN H.K., Exercise can provide protection against bone loss and prevent the decrease in mechanical strength of femoral neck in ovariectomized rats, J. Bone Miner. Res., Oct. 1994, Vol. 9, No. 10, 1559–1564.
• [10] PENG Z.Q., VÄÄNÄNEN H.K., TUUKKANEN J., Ovariectomy – induced bone loss can be affected by different intensities of treadmill running exercise in rats, Calcified Tissue International, Missouri, 1997, Vol. 60, 441–448.
• [11] NELSON M.E., FIATARONE M.A. et al., Effect of high intensity, strength training on multiple risk factors for osteoporotic fractures, JAMA, 1994, Vol. 272, 1909–1914.
• [12] ZARROW M.X. et al., Experimental endocrinology, a source book of basic technique, Academic press, New York, 1964, Vol. 1, 39–40.
• [13] NAKAJIMA D., KIM C.S., OH T.W., YANG C.Y., NAKA T., IGAWA S., OHTA F., Suppressive effects of genistein dosage and resistance exercise on bone loss in ovariectomized rats, J. Physiol. Anthropol., 2001, Vol. 20, No. 5, 285–291.
• [14] IWAMOTO J., TAKEDA T., ICHIMURA S., Effect of moderate intensity exercise on tibial bone mass in mature ovariectomized rats: bone histomorphometry study, Keio J. Med., 1998, Vol. 47, 162–167.