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The application of the cell method in a clinical assessment of bone fracture risk

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Języki publikacji
EN
Abstrakty
EN
The aim of this paper is to introduce a new technique for in vivo quantification of bone structure fracture risk. The elastic properties of the architecture obtained from bone digital radiographic images are determined using the cell method. Compression tests are simulated and the results of the numerical analysis are indexed. Such an index is considered to be indicative of the bone structure capabilities. The first clinical validation was carried on at CSMMO, Centro Studi Malattie Metaboliche dell’Osso (Gorizia, Italy), showing that this technique can improve the diagnosis and help a physician in the identification of an actual fracture risk. The examination is not expensive, uses instrumentation that is widely available and therefore could be easily introduced in clinical use as a complement to the current osteoporosis diagnosis methodologies.
Rocznik
Strony
35--39
Opis fizyczny
Bibliogr. 11 poz., rys., wykr.
Twórcy
autor
autor
  • University of Trieste, Dipartimento di Energetia, Italy
Bibliografia
  • [1] International Osteoporosis Foundation, http://www.iofbonehealth.org/home.html
  • [2] National Osteoporosis Foundation (NOF), http://www.nof.org
  • [3] Consensus development conference. Diagnosis, prophylaxis and treatment of osteoporosis, AM J Med., 1993, 94, 646–650.
  • [4] ZYSSET P.K., A review of morphology-elasticity relationhips in human trabecular bone: theories and experiments, J. Biomechanics, 2003, 36, 1469–85.
  • [5] NIEBUR G.L. et al., High resolution finite element models with tissue strength asymmetry accurately predict failure of trabecular bone, J. Biomechanics, 2000, 33, 1575– 83.
  • [6] COSMI F., DREOSSI D., Numerical and experimental analysis of bone microarchitectures, 22th DAS, Monticelli Terme (Parma), Italy, 28.09–01.10.2005.
  • [7] BREAR K., CURREY J.D., RAINES S., SMITH K.J., Density and temperature effects on some mechanical properties of cancellous bone, Engineering in Medicine, 1988, 17, 163– 167.
  • [8] TONTI E., A direct discrete formulation of field laws: the cell method, CMES, Computer Modeling in Engineering & Sciences, 2001, 2, 237–258.
  • [9] COSMI F., Numerical solution of plane elasticity problems with the cell method, CMES, Computer Modeling in Engineering & Sciences, 2001, 2, 365–372.
  • [10] COSMI F., DI MARINO F., Modelling of the mechanical behaviour of porous materials: A new approach, Acta of Bioengineering and Biomechanics, 2001, 3, 55–65.
  • [11] COSMI F., Numerical Modeling of Porous Materials Mechnical Behaviour with the Cell Method, Proc. of Second M.I.T. Conference on Computational Fluid and Solid Mechanics, June 17–20, 2003, Massachusetts Institute of Technology, Cambridge, MA, U.S.A.
  • [12] COSMI F., Two-dimension estimate of effective properties of solid with random voids, Theoretical and Applied Fracture Mechanics, Elsevier Science, 204, 42, 183–186.
  • [13] Agency for Healthcare Research and Quality, US Department of Health and Human Services, http://www.guideline.org
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BPB1-0032-0025
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