Human cardiovascular system with heat failure under baroreflex control (numerical model)

• Autorzy: Prevorovská S. , Musil J. , Maršik F.
• Języki publikacji: EN

Abstrakty

EN

Numerical simulation of the cardiovascular haemodynamics has become a useful tool of the surgeon who diagnoses cardiovascular diseases and recommends the way of their medical treatment. The numerical model of the cardiovascular system of pulsating type imitating the electrochemical and mechanical activity of heart muscle and being under a short-term baroreflex control has been implemented to diagnose more accurate a patient's haemodynamic profile. This model enables thus the simulation of the haemodynamic reaction due to the baroreflex response at various perturbations in the circulatory system. The haemodynamic behaviour of the cardiovascular system in the cases of the heart failure as a consequence of the left-ventricular hypocontractility, with the usage of the heart support device and the circulatory failure caused by haemorrhagic shock are demonstrated.

Słowa kluczowe

EN

human cardiovascular system; baroreflex control; haemorrhagic shock; heart support; numerical simulation

PL

układ krążenia; badania medyczne; symulacja numeryczna; serce

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 2001
• Tom: Vol. 3, nr 1
• Strony: 39--52
• Opis fizyczny: Bibliogr. 8 poz., rys., tab., wykr.

Twórcy

autor

Prevorovská S.

• Institute of Thermomechanics CAS, Prague 8, 182-100 Dolejškova 5, Czech Republic

autor

Musil J.

• Institute of Thermomechanics CAS, Prague 8, 182-100 Dolejškova 5, Czech Republic

autor

Maršik F.

• Institute of Thermomechanics CAS, Prague 8, 182-100 Dolejškova 5, Czech Republic

Bibliografia

• [1] BEELER G.W., REUTER H., Reconstruction of the action potential of ventricular myocardial fibres, J. Physiol. (Lond.), 1977, 268, pp. 177-210.
• [2] SIMURDA J., SIMURDOVA M., BRAVENY P., CHRISTE G., Control of cardiac perfonnance by Ca­turnover, Molecular and Cellular Biochemistry, 1996, 160/161, pp. 5-12.
• [3] PREVOROVSKA S., MARiiiK F., The influence of the membrane transport on the heart mechanical activity, Engineering mechanics '99, Svratka, May 17-20, 1999, pp. 575-580.
• [4] PREVOROVSKA S., MARSIK F., MUSIL J., Pressure generation by chemical reaction in the human cardiovascular system, Engineering Mechanics, 1997, Vol. 4, No.3, pp. 147-154.
• [5] SEIDEL H. , HERZEL A., Modelling heart rate variability due to respiration and barorejlex, [in:] Modelling the Dynamics of Biological Systems, ed. by E. Mosekilde and O.G. Mouritsen, Springer ­ Verlag, Berlin, 1995, pp. 205-229.
• [6] Heart failure simulation observations, http://www.bme.jhu.edu/courses/580.421/hw5/solution.html.
• [7] NEUMANN . S., Modelling acute hemorrhage in the human cardiovascular system, A dissertation bioengineering, University of Pensylvania, 1996.
• [8] WILSON I.H., BASKETT O.J.F., The diagnosis and treatment of haemorrhagic shock, Practical Procedures, Issue 1, Article 4, 1992.