New bone implant material with calcium sulfate and Ti modified hydroxyapatite

• Autorzy: Ślósarczyk A. , Czechowska J. , Paszkiewicz Z. , Zima A.
• Języki publikacji: PL

Abstrakty

EN

Purpose: In this work, calcium sulfate hemihydrate (CSH) was combined with titanium doped hydroxyapatite (TiHA) to develop a novel bone cement. Results of previous studies showed that bioactive potential of titanium modified hydroxyapatite ceramics is higher than that of pure HA. Calcium sulfate hemihydrate is also considered as a safe, biocompatible material, however it has been criticized for its rapid resorption. Combination of these materials may result in new cement type material with surgical handiness and selective resorption. Design/methodology/approach: TiHA was obtained by a wet method. Three compositions with different CSH:TiHA weight ratios, namely 3:2, 2:3 and 1:4 were examined. Pure CSH was used as a reference. Distilled water and Na2HPO4 solutions were applied as liquid phases. The study presents the setting time (Gillmore apparatus), phase composition (XRD), microstructure (SEM), porosity (mercury porosimetry) and compressive strength of the obtained new, cement type, implant material. Findings: Initial (I) and final (F) setting times of the obtained cements differed in the range of 2-16 min (I) and 4-75 min (F). The phase composition of the hardened cement bodies characterized by XRD method revealed the presence of calcium sulfate dihydrate (CSD) and hydroxyapatite. Scanning electron microscopy images show excellent bonding between needle-like CSD crystals and apatitic phase. Porosity of the final samples varied from 49 to 59% with pore size diameter from 5 nm to 3.0 ěm. Compressive strength of the samples differed in the range of 3.81-7.58 MPa. Research limitations/implications: The obtained results suggest that CSH-TiHA cements have the potential to be applied in bone substitution and for delivery of drugs. Bioactivity and biodegradation of the studied materials should be checked. Originality/value: According to our knowledge, these are the first studies concerning surgical handiness of bone implant materials based on calcium sufate hemihydrate and titanium doped hydroxyapatite. The cement type composites are biocompatible, shapeable and easy to apply and adapt in bone defects.

Słowa kluczowe

EN

bone substitute; hydroxyapatite; calcium sulfate

• Wydawca: International OCSCO World Press
• Czasopismo: Journal of Achievements in Materials and Manufacturing Engineering
• Rocznik: 2010
• Tom: Vol. 43, nr 1
• Strony: 170--177
• Opis fizyczny: Bibliogr. 21 poz., rys., tabl.

Twórcy

autor

Ślósarczyk A.

autor

Czechowska J.

autor

Paszkiewicz Z.

autor

Zima A.

• AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, Poland,

Bibliografia

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