HPLC study of the pharmacokinetics of K-203

• Autorzy: Kalász H. , Laufer R. , Szegi P. , Kuca K. , Musilek K. , Tekes K.
• Języki publikacji: EN

Abstrakty

EN

The pharmacokinetics of K-203, a recently synthesized bis-pyridinium aldoxime, have been investigated by reversed-phase HPLC. The K-203 content of serum samples was monitored by HPLC with ultraviolet absorbance detection at 286 nm. The low concentration of K-203 in samples of brain, eyes, and cerebrospinal fluid was also determined by HPLC; quantitative evaluation was possible by use of an amperometric detector.

Słowa kluczowe

EN

HPLC; K-203; pharmacokinetics; serum; brain; CSF; eyes

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2008
• Tom: Vol. 20, no. 4
• Strony: 575--584
• Opis fizyczny: Bibliogr. 18 poz., rys., tab.

Twórcy

autor

Kalász H.

autor

Laufer R.

autor

Szegi P.

autor

Kuca K.

autor

Musilek K.

autor

Tekes K.

• Semmelweis University Department of Pharmacology and Pharmacotherapy Budapest Hungary Semmelweis University Department of Pharmacodynamics Budapest Hungary University of Defence Centre of Advanced Studies, Faculty of Military Health Sciences Hradec Kralo,

Bibliografia

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