Tytuł artykułu
Autorzy
Wybrane pełne teksty z tego czasopisma
Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
A new simple, precise, accurate, and selective thin-layer chromatographic (TLC) method has been developed for simultaneous analysis of atenolol and lercanidipine hydrochloride in a tablet dosage form. Chromatographic separation was achieved on aluminum foil plates precoated with silica gel 60F 254 , with toluene-methanoltriethylamine 3.5:1.5:0.1 (v/v) as mobile phase. Detection was performed densitometrically at 275 nm. The R F of atenolol and lercanidipine hydrochloride were 0.24 and 0.68, respectively. The reliability of the method was assessed by evaluation of linearity (2000-12000 ng per band for atenolol and 400-2400 ng per band for lercanidipine hydrochloride), accuracy (98.94 š 0.30% for atenolol and 99.75 š 0.69% for lercanidipine hydrochloride), and specificity, in accordance with ICH guidelines. The method can be used for routine simultaneous analysis of atenolol and lercanidipine hydrochloride in pharmaceutical formulations.
Słowa kluczowe
Czasopismo
Rocznik
Tom
Strony
463--473
Opis fizyczny
Bibliogr. 17 poz., rys., tab.
Twórcy
autor
autor
autor
- R.C. Patel College of Pharmacy Department of Pharmaceutical Chemistry Shirpur Dist: Dhule (M.S.) India 425 405, atulshirkhedkar@rediffmail.com
Bibliografia
- [1] M.J. O’Neil, The Merck Index, 14th edn, Merck Research Laboratories, White-house Station, NJ, 2006, p. 142
- [2] Indian Pharmacopoeia, Government of India, Ministry of Health and Family Welfare, Controller of Publications, Delhi, 1996, pp. 72–73
- [3] British Pharmacopoeia, Vol. I, The stationary office, London, 2005, pp. 179–181
- [4] United States Pharmacopeia, 28th edn, The United States Pharmacopeial Convention, Rockville, MD, 2005, p. 193
- [5] A.V. Kasture and M. Ramteke, Indian J. Pharm. Sci., 68 (3), 394 (2006)
- [6] S.M. Al-Ghannam, J. Pharm. Biomed. Anal., 40 , 151 (2006)
- [7] T. Sivakumar, P. Venkatesan, R. Manavalan, and K. Valliappan, Indian J. Pharm. Sci., 69 (1), 154 (2007)
- [8] R.K. Barman, M.A. Islam, M. Ahmad, M.I. Ibnewahed, R. Islam, A. Khan, M.B. Hossain, and B.M. Rahman, Pak. J. Pharm. Sci., 20 (4), 274 (2007)
- [9] L.R.P. de Abreu, S.A.C. de Castro, and J. Pedrazzoli Jr., AAPS Pharm. Sci. 5 (2), article 21 (2003)
- [10] A.P. Argekar and S.G. Powar, J. Pharm. Biomed. Anal., 21 (6), 1137 (2000)
- [11] S.R. Sathe and S.B. Bari, Acta Chromatogr., 19 , 270 (2007)
- [12] S.C. Sweetman (Ed.) Martindale — The Complete Drug Reference, Vol. I, Pharmaceutical Press, 2007, p. 1189
- [13] A.A. Shirkhedkar, P.V. Deore, and S.J. Surana, Biosci. Biotech. Res. Asia, 4 (2), 753 (2007)
- [14] S. Mihaljica, D. Radulovic, and J. Trbojevic, Chromatographia, 61 (1/2), 25 (2005)
- [15] A. Alvarez-Lueje, S. Pujol, J.A. Squella, and L.J. Nunez-Vergara, J. Pharm. Biomed. Anal., 31 , 1 (2003)
- [16] I.I. Salem, J. Idrees, J.I. Al Tamimi, and P. Farina, J. Chromatogr. B, 803 , 201 (2004)
- [17] ICH Guidelines Q2B, Validation of Analytical Procedures — Methodology, 1996.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BATE-0001-0036