HPLC analysis of magnolol and honokiol in Magnoliae Cortex after solvent sublation

• Autorzy: Dong H. R. , Liu X. Q.
• Języki publikacji: EN

Abstrakty

EN

A novel method for separating and concentrating magnolol and honokiol from Magnoliae Cortex by solvent sublation and analysis of the compounds by highperformance liquid chromatography (HPLC) has been established. The optimum conditions for solvent sublation were use of n-butanol as sublation solvent, sample solution at pH 2, nitrogen flow 50 mL min^-1, and sublation time 50 min. The floating product obtained under the optimum conditions was determined by HPLC analysis on a C₁₈ reversed- phase column, with 22:78 (%, v/v) water-methanol as isocratic mobile phase at a flow rate of 1.00 mL min-1. When the method was used for quantification of magnolol and honokiol in Magnoliae Cortex recovery ranged from 98.1 to 106.1%, RSD was from 3.07 to 4.80%, and LOD for honokiol and magnolol were 0.94 and 1.14 ng mL^-1, respectively.

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2008
• Tom: Vol. 20, no. 1
• Strony: 147--156
• Opis fizyczny: Bibliogr. 27 poz., rys., tab.

Twórcy

autor

Dong H. R.

autor

Liu X. Q.

• College of Science, Beijing University of Chemical Technology, Beijing 100029, China Department of Chemistry, Qinghai Normal University, Xining 810008, China

Bibliografia

• [1] Committee of National Pharmacopoeia, Pharmacopoeia of People’s Republic of China, Press of Chemical Industry, Beijing, 2005, Vol. 1, p. 176
• [2] J. Park, J. Lee, E.S. Jung, Y. Park, K. Kim, B. Park, K.S. Jung, E. Park, J. Kim, and D. Park, Eur. J. Pharm., 496, 189 (2004)
• [3] J.P. Wang, M.F. Hsu, S.L. Raung, C.C. Chen, J.S. Kuo, and C.M. Teng, Naunyn- Schmiedeberg’s Arch. Pharmacol., 346, 707 (1992)
• [4] M. Ogata, M. Hoshi, K. Shimotohno, S. Urano, and T. Endo, J. Am. Oil Chem. Soc., 74, 557 (1997)
• [5] K. Ikeda, Y. Sakai, and H. Nagase, Phytother. Res., 7, 933 (2003)
• [6] K.Y. Ho, C.C. Tsai, C.P. Chen, J.S. Huang, and C.C. Lin, Phytother. Res., 15, 130 (2001)
• [7] S.K. Tsai, C.H. Huang, S.S. Huang, L.M. Hung, and C.Y. Hong, Pharmacology, 59, 227 (1999)
• [8] M.K. Pyo, Y.Y. Lee, and H.S. Yun-Choi, Arch. Pharm. Res., 25, 325 (2002)
• [9] J. Ueda, N. Monna, and K. Ohsawa, Yakugaku Zasshi, 113, 155 (1993)
• [10] G. Chen, X.J. Xu, Y.Z. Zhu, L.Y. Zhang, and P.Y. Yang, J. Pharm. Biomed. Anal., 41, 1479 (2006)
• [11] K. Suto, Y. Ito, K. Sagara, and H. Itokawa, J. Chromatogr. A, 786, 366 (1997)
• [12] A. Kotani, S. Koilma, H. Hakwata, D. Jin, and F. Kusu, Chem. Pharm. Bull (Tokyo), 53, 319 (2005)
• [13] Y.C. Lee, C.Y. Huang, K.C. Wen, and T.T. Suen, J. Chromatogr. A, 692, 137 (1995)
• [14] X.N. Wu, X.G. Chen, and Z.D. Hu, Talanta, 59, 115 (2003)
• [15] F. Sebba, Ion Flotation, Elsevier, New York, 1962, p. 112
• [16] Y.J. Lu and X.H. Zhu, Talanta, 57, 891 (2002)
• [17] Y.S. Kim, J.H. Shin, Y.S. Choi, W. Lee, and Y.I. Lee, Microchem. J., 68, 99 (2001)
• [18] H.R. Dong and X.Y. Yao, Anal. Lett., 21, 1065 (1988)
• [19] H.R. Dong, S.Z. Yang, and J.L. Liu, Anal. Sci., 5, 601 (1989)
• [20] Q. Cheng and H.R. Dong, Microchim. Acta, 150, 59 (2005)
• [21] J.S. Smith, K.T. Valsaraj, and L.J. Thibodeaux, Ind. Eng. Chem. Res., 35, 1688 (1996)
• [22] J.S. Smith, K.T. Valsaraj, and L.J. Thibodeaux, Ind. Eng. Chem. Res., 35, 1700 (1996)
• [23] J.S. Smith and K.T. Valsaraj, Ind. Eng. Chem. Res., 36, 903 (1997)
• [24] J.S. Smith and K.T. Valsaraj, Chem. Eng. Prog., 94, 69 (1998)
• [25] B.G. Bryson and K.J. Valsaraj, J. Hazard. Mater., 82, 65 (2001)
• [26] Y.J. Lu, J.H. Liu, J. Tang, B. Wei, and X.L. Zhang, J. Colloid Interface Sci., 283, 278 (2005)
• [27] H.Q Wei, E.B. Liu, and H.B Ji, J. Shijiazhuang College, 7, 1 (2005).