Detecting epileptogenesis in power variant domains

• Autorzy: Lewis R. A. , Parks B. , Shmueli D. , Capinst S.
• Języki publikacji: EN

Abstrakty

EN

This paper presents the merging of two sets of experiments in the continuing endeavor to mine epileptiform activity from Electroencephalograms (EEG). The goal is to develop robust classification rules for identifying epileptiform activity in the human brain. We present advancements using the author's proprietary developed spectral analysis software to link power spectra of rat EEGs experiencing epilepsy seizures with the authors DFA algorithm and their MATLAB spectral analysis. Our system links 1) power spectra of seizures, in sleep, spike and seizure states, with 2) Deterministic Finite Automata (DFA). Combining power spectra with DFA to correctly predict and identify epileptiform activity (spikes) and epileptic seizures opens the door to creating classifiers for seizures. We also present a DFA that separates the states between seizure and nonseizure using robust testing and additional algorithms to increase the rigor when the methodology analyses noisy signals. Our results show optimal identification of seizures even when significant artifact and noise is present in the polyphonic domain. Herein we present a dual methodology that increases epileptoid identification in a noisy domain that links time and frequency domain components from MATLAB and proprietary software to clinical epileptiform activity.

Słowa kluczowe

EN

intracortical electroencephalograms automata; epilepsy; Fourier transforms; rough sets

• Wydawca: Systems Research Institute, Polish Academy of Sciences
• Czasopismo: Control and Cybernetics
• Rocznik: 2011
• Tom: Vol. 40, no 2
• Strony: 293--314
• Opis fizyczny: Bibliogr. 37 poz., il.

Twórcy

autor

Lewis R. A.

autor

Parks B.

autor

Shmueli D.

autor

Capinst S.

• Departments of Pediatrics & Neurology, University of Colorado Denver Anschutz Medical Campus, Colorado 80045, USA

Bibliografia

• Bandeira,F., Lent,R. andHerculano-Houzel,S. (2009) Changing numbers of neuronal and non-neuronal nells underlie postnatal brain growth in the rat. Proceedings of The National Academy of Sciences of the USA 106(33), 14108-14113.
• Bertram, E.H., Wiliamson, J.M., Cornett, J.F., Spradlin, S. and Chen, Z.F. (1997) Design and construction of a long-term continuous video-EEG monitoring unit for simultaneous recording of multiple small animals. Brain Research Protocols 2 (1), 85-97.
• Buckmaster, P.S. and Dudek, F.E. (1998) Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats. The Journal of Comparative Neurology 385(3), 385-404.
• Eder,H.G., Jones,D.B. and Fisher,R.S. (1997) Diazepam prophylaxis for bicuculline-induced seizures: a rat dose-response model. Epilepsia 38, 516.
• Firpi, H., Goodman, E. and Echauz, J. (2005) Genetic Programming Artificial Features with Applications to Epileptic Seizure Prediction. Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference, Shanghai. IEEE, 4510-4513.
• Fisher, R.A. (1935) The Logic of Inductive Inference. J. R. Stat. Soc. A, 98.
• Geva,A.B. andKerem,D.H. (1998) Forecasting generalized epileptic seizures from the EEG signal by wavelet analysis and dynamic unsupervised fuzzy clustering. IEEE Transaction of Biomed Engineering, 45, 1205-1216.
• Gluckman,B.J., Nguyen,H., Weinstein, S.L., Schiff, S.J. (2006) Adaptive electric field control of epileptic seizures. The Journal of neuroscience: the official journal of the Society for Neuroscience, 21(2), 590-600.
• Hellier, J.,White,A.M.,Williams,P.A., Dudek,E.F. and Staley,K.J. (2009) NMDA receptor-ediated long-term alterations in epileptiform activity in experimental chronic epilepsy. Neuropharmacology 56(2), 414-421.
• Korbo, L. (1990) An Efficient Method for Estimating the Total Number of Neurons in Rat Brain Cortex. Journal of Neuroscience Methods, 31(2), 93-100.
• Lehnertz, K. and Elger, C. (1995) Spatio-temporal dynamics of the primary epileptogenic area in temporal lobe epilepsy characterized by neuron al complexity loss. Electroencephalography and Clinical Neurophysiology, 95, 108-117.
• Lewis, R., Cohen, A., Wenxin, J. and Raś, Z.W. (2008) Hierarchical Tree for Dissemination of Polyphonic Noise. Rough Sets and Current Trends in Computing. Proceedings of the 6th International Conference on RSCTC ‘08, Akron, OH. Springer-Verlag,Berlin-Heidelberg, 448-456.
• Lewis, R. and Raś, Z.W. (2007) Rules for Processing and Manipulating Scalar Music Theory. Proc. IEEE Computer Society April 26-28 MUE 2007 in Seoul Korea, 819-824.
• Lewis, R., Shmueli, D. and White, A.M. (2010) Deterministic Finite Automata in the Detection of EEG Spikes and Seizures. In: P.R. Cohen, N.M. Adams and M.R. Berthold, eds., Advances in Intelligent Data Analysis IX. LNCS 6065, Springer, 103-113.
• Lewis, R. and White, A.M. (2010) Seizure Detection Using Sequential and Coincident Power Spectra with Deterministic Finite Automata. In: Proceedings of Bioinformatics and Computational Biology (BIOCOMP) 2010, Las Vegas Nevada, Volume II. World Academy of Science, 481-488.
• Lewis, R. and Wieczorkowska, A. (2007) Categorization of Musical Instrument Sounds Based on Numerical Parameters. In: Proceedings of RSEISP, 15th International Conference on Conceptual Structures, ICCS 2007, Sheffield, UK. LNAI 4604, Springer Berlin-Heidelberg, 784-792.
• Lewis, R., Zhang, X. and Raś, Z.W. (2007) MIRAI: Multi-hierarchical FSTree Based Music Information Retrieval System. LNAI [Volume no..??], Springer, 28-30.
• Litt, B., Esteller, R., Echauz, J., D’Alessandro, M., Shor, R., Henry, T., Pennell, P., Epstein, C., Bakay, R. and Dichter, M. (2001) Epileptic Seizures May Begin Hours in Advance of Clinical Onset. A Report of Five Patients. Neuron, 30(1), 51-64.
• Molnar, P. and Nadler, J.V. (1999) Mossy Fiber-Granule Cell Synapses in the Normal and Epileptic Rat Dentate Gyrus Studied With Minimal Laser Photostimulation. The Journal of Neurophysiology, 82(4), 1883-1894.
• Mormann, F., Andrzejak, R.G., Kreuz, T., Rieke, Ch., David, P., Elger, Ch.E. and Lehnertz, K. (2003) Automated detection of a preseizure state based on a decrease in synchronization in intracranial electroencephalogram recordings from epilepsy patients. Phys. Rev. E, 67(2):021912, doi:10.1103/PhysRevE.67.021912.
• Niedermeyer, E. and da Silva, F.L. (1999) Electroencephalography, Basic Principles, Clinical Applications & Related Fields. Williams and Wilkins, Baltimore (MD).
• Pan,Y., Ge, S.S., Tang,F.R. and Mamun,A.A. (2007) Detection of epileptic spike-wave discharges using SVM. In: Proceedings of the 2007 IEEE International Conference on Control Applications, Suntec City, Singapore. IEEE, 467-472.
• Pawlak, Z. (1991) Information Systems - Theoretical Foundations. Information Systems Journal, 6, 205-218.
• Racine, R.J. (1972) Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr Clin Neurophysiol, 32, 281-294.
• Raś, Z.W. and Dardzińska, A. (2005) Intelligent query answering. In: J. Wang, ed., Encyclopedia of Data Warehousing and Mining. Idea Group, 639-643.
• Raś, Z.W., Tzacheva, A. and Tsay, L. (2005) Action Rules. In: J. Wang, ed., Encyclopedia of Data Warehousing and Mining. Idea Group, 1-5.
• Raś, Z.W. and Wieczorkowska, A. (2000) Action Rules: how to increase profit of a company. Principles of Data Mining and Knowledge Discovery, 1910, 87-592.
• Salant, Y., Gath, I. and Henriksen, O. (1998) Prediction of epileptic seizures from two-channel EEG. Medical and Biological Engineering and Computing, 36, 549-556.
• Schiff, S.J., Jerger, K., Duong, D.H., Chang, T., Spano, M.L. and Ditto, W.L. (1994) Controlling chaos in the brain. Nature, 370(6491), 615-620.
• Stein, A.G., Eder, H.G., Blum, D.E., Drachev, A. and Fisher, R.S. (2000) An automated drug delivery system for focal epilepsy. Epilepsy Res, 39(2), 103-114.
• Tsay, L. andRaś, Z.W. (2005) Action Rules Discovery System DEAR Method and Experiments. Journal of Experimental and Theoretical Artificial Intelligence, 17,1-2, 119-128.
• Velasco,M., Velasco,F.V., Velasco,A.L., Boleaga,B., Jimenez, F., Brito, F. and Marquez, I. (2005) Double-blind randomized controlled pilot study of bilateral cerebellar stimulation for treatment of intractable motor seizures. Epilepsia, 46(7), 1071-81.
• White,A.M., Williams,P.A., Ferraro,D.J., Clark, S., Kadam, S.D., Dudek, F.E. and Staley, K.J. (2006) Efficient unsupervised algorithms for the detection of seizures in continuous EEG recordings from rats after brain injury. Journal of Neuroscience Methods, 152(1-2), 255-266, ISSN 0165-0270, doi:DOI: 10.1016/j.jneumeth.2005.09.014.
• Williams, P., White, A.M., Ferraro, D., Clark, S., Staley, K. and Dudek, F.E. (2006) The use of radiotelemetry to evaluate electrographic seizures in rats with kainate-induced epilepsy. Journal of Neuroscience Methods, 155(1), 39-48, ISSN 0165-0270, doi:DOI: 10.1016/j.jneumeth. 2005.12.035.
• Williams, P.A., Hellier, J., White, A.M., Clark, S., Ferraro, D., Swiercz, W., Dudek, E.F. and Staley, K.J. (2009) Development of Spontaneous Recurrent Seizures after Kainate-Induced Status Epilepticus. The Journal of Neuroscience, 29(7), 2103-2112.
• Williams,P.A., Hellier, J., White,A.M., Staley,K. and Dudek,E.F. (2007) Development of Spontaneous Seizures after Experimental Status Epilepticus: Implications for Understanding Epileptogenesis. Epilepsia (Series 4), 48, 157-163.
• Williams, R.W. and Herrup, K. (1988) The Control of Neuron Number. The Annual Review of Neuroscience, 11, 423-453.