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Tytuł artykułu
Autorzy
Wybrane pełne teksty z tego czasopisma
Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
Cellular oxidative stress has been implicated as a key mechanism of cell differentiation provoked by several compounds (doxorubicins, fibrades, edelfosine). Phenylacetate and its derivatives in submillimolar to millimolar concentrations induce cell differentiation. Ion-exclusion chromatography is widely used for separation and analysis of weak acids. We applied it to the analysis of phenylacetic acids and to the determination of the hydroxyl radical-trapping potential of some of these compounds. Their total antioxidant potential for peroxy radicals was also measured using a photometric method. It was found that phenylacetates are weak antioxidants and in the concentrations which induce cell differentiation effects may substantially reinforce intracellular antioxidative potential.
Słowa kluczowe
Czasopismo
Rocznik
Tom
Strony
258--268
Opis fizyczny
Bibliogr. 34 poz., rys.
Twórcy
autor
- Meat and Fat Research Institute, Jubilerska 4, 04-190 Warsaw, Poland
autor
- Medical Research Center, Polish Academy of Sciences, Laboratory of Experimental Pharmacology, ul. Pawińskiego 5, 03-187 Warszawa, Poland
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BAT3-0028-0084