Chromatographic behaviour of antibiotics on thin layers of an inorganic ion-exchanger

• Autorzy: Husain S. W. , Ghoulipour V. , Sepahrian H.
• Języki publikacji: EN

Abstrakty

EN

The chromatographic behaviour of amoxicillin, ampicillin, cepha-lexin, cloxacillin, doxycycline, tetracycline, erythromycin, gentamycin, stre-ptomycin, and co-trimoxazole has been studied on thin layers of titanic silicate inorganic ion-exchanger with organic, aqueous, and mixed aqueous–organic mobile phases. Rapid separations of one antibiotic from numerous other antibiotics have been achieved, as have many binary and ternary separations. Salting-out TLC using aqueous ammonium sulphate solutions revealed the dependence of RF values on the concentration of salt in the mobile phase, and the existence of a linear relationship between RM and molarity of (NH4)2SO4 for some antibiotics. The effect of varying the vo-lume ratio of the binary mobile phase methanol–0.1 M formic acid on the RF values of the antibiotics has also been studied.

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2004
• Tom: No. 14
• Strony: 102--109
• Opis fizyczny: Bibliogr. 32 poz., rys., tab.

Twórcy

autor

Husain S. W.

• Department of Applied Chemistry, Faculty of Chemistry, University of Tarbiat Moallem, 49 Mofatteh Avenue, Tehran-15614, Iran

autor

Ghoulipour V.

• Department of Applied Chemistry, Faculty of Chemistry, University of Tarbiat Moallem, 49 Mofatteh Avenue, Tehran-15614, Iran

autor

Sepahrian H.

• Department of Applied Chemistry, Faculty of Chemistry, University of Tarbiat Moallem, 49 Mofatteh Avenue, Tehran-15614, Iran

Bibliografia

• [1] P.R. Bonchev, P. Papazova, M. Confino, and D. Dimova, Mikrochim. Acta, 111, 459 (1984)
• [2] R.C. Evangelista and E.E.S. Schapoval, Rev. Cienc. Farm., 5, 21 (1983); Anal. Abs., 6E37 (1985)
• [3] J. Kusnier and K. Barna, Z. Anal. Chem., 271, 288 (1974)
• [4] N.M. Alyokov, Zh. Anal. Khim., 36, 1387 (1981)
• [5] C.G. Perez, I.G. Martin, and B.R.V. De Aldana, J. Pharm. Biomed. Anal., 9, 383 (1991)
• [6] L.J. Nunez-Vergara, J.A. Sequella, and M.M. Silva, Farmaco, Ed. Prat., 35, 409 (1980)
• [7] M.C. Caturla, E. Cusido, and D. Westerlund, J. Chromatogr., 593, 69 (1992)
• [8] L. Soltes, Biomed. Chromatogr., 13, 3 (1999)
• [9] A. Aghazadeh and G. Kazemifard, J. Pharm. Biomed. Anal., 25, 325 (2001)
• [10] F. Kreuzig in J. Sherma and B. Fried (eds) Handbook of Thin-Layer Chromatography, Dekker, New York, 1990, pp. 407–417
• [11] J. Sherma, Anal. Chem., 64, 134R (1992); 66, 67R (1994); 68, 1R (1996); 70, 7R (1998);72, 9R (2000)
• [12] G. Misztal and R. Skibiński, J. Planar Chromatogr., 14, 300 (2001)
• [13] G. Indrayanto, T.K. Sia, and L. Wuladari, J. Planar Chromatogr., 14, 456 (2001)
• [14] R. Bhushan and M. Arora, J. Planar Chromatogr., 14, 435 (2001)
• [15] S.P. Kumar, P.V. Srinivas, and J.M. Rao, J. Planar Chromatogr., 15, 128 (2002)
• [16] V. Ghoulipour and S.W. Husain, Anal. Sci., 16, 1079 (2000)
• [17] V. Ghoulipour and S.W. Husain, J. Planar Chromatogr., 13, 354 (2000)
• [18] V. Ghoulipour and S.W. Husain, J. Planar Chromatogr., 12, 378 (1999)
• [19] S.W. Husain and A. Mirzaie, Chromatographia, 45, 347 (1997)
• [20] S.W. Husain, A. Avanes, and V. Ghoulipour, J. Planar Chromatogr., 9, 67 (1996)
• [21] S.W. Husain and Z. Ishghy, J. Liq. Chromatogr., 15, 1681 (1992)
• [22] S.W. Husain, Z. Ishghy, and M. Chaloosi, J. Planar Chromatogr., 3, 271 (1990)
• [23] S.W. Husain and V. Ghoulipour, J. Planar Chromatogr., 2, 474 (1989)
• [24] T.J. Janjic, V.M. Zivkovic-Radovanovic, and M.B. Celap, J. Serb. Chem. Soc., 62, 1 (1997)
• [25] A. Resplandy, C.R. Acad. Sci., 238, 2527 (1954)
• [26] I. Jakubec, Collect. Czech. Chem. Commun., 26, 1072 (1961)
• [27] A.O. Kuhn and M. Lederer, J. Chromatogr., 406, 311 (1987)
• [28] A.O. Kuhn and M. Lederer, J. Chromatogr., 440, 165 (1988)
• [29] G. Vuckovic, D. Miljevic, T.J. Janjic, and M.B. Celap, J. Chromatogr., 609, 427 (1992)
• [30] T.J. Janjic, V.M. Zivkovic, and M.B. Celap, Chromatographia, 38, 447 (1994)
• [31] C. Horvath, W.R. McLander, and I. Molnar, J. Chromatogr., 125, 129 (1976)
• [32] A. Mahum and C. Horvath, J. Chromatogr., 203, 53 (1981)