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Abstrakty
RPTLC retention characteristics have been determined for two series of 1-alkyl-4(1H)-quinolinones with 3-alkylthio and 3-alkylsulfinyl groups. Experimentally obtained measures of lipophilicity, expressed as RM0 values, were compared with values of log P calculated by a computational method.
Słowa kluczowe
Czasopismo
Rocznik
Tom
Strony
243--247
Opis fizyczny
Bibliogr. 12 poz., tab.
Twórcy
autor
- Department of Organic Chemistry, The Medical University of Silesia, 41-200 Sosnowiec, Jagiellońska 4, Poland
autor
- Department of Organic Chemistry, The Medical University of Silesia, 41-200 Sosnowiec, Jagiellońska 4, Poland
autor
- Institute of Chemistry, University of Silesia, 40-006 Katowice, Szkolna 9, Poland
Bibliografia
- [1] U. Petersen, S. Bartel, K-D. Bremm, T. Himmler, A. Krebs, and T. Schenke, Bull. Soc. Chim. Belg., 105, 683 (1996)
- [2] R.V. Davies, J. Fraser, and K.J. Nichol, Eur. Patent 0 206 616 A2 (1986); Chem. Abs., 107 (1987) P5881g
- [3] K. Ikezono, S. Fujita, M. Umezato, E. Hosoki, Y. Toba, A. Kusunoki, and S. Shintani, Arzneim. – Forsch., 42, 1200 (1992)
- [4] R.V. Davies, J. Fraser, K.J. Nichol, R. Parkinson, M.F. Sim, and D.B. Yates, Ger. 30 11 994 A1 (16.10.1980)
- [5] H. Kubinyi, Pharm. Ztg. Wiss., 4, 265 (1991)
- [6] C. Martorell, A.C. Calpena, E. Escribano, J.M. Poblet, and J. Freixas, J. Chromatogr. A, 655, 177 (1993)
- [7] G.L. Biaggi, A.M. Barbaro, A. Sapone, and M. Recanatini, J. Chromatogr., 625, 392 (1992)
- [8] M. Rudnik and A. Maślankiewicz, Heterocycles, 51, 2731 (1999)
- [9] R.V. Davies, J. Fraser, K.J. Nicol, R. Parkinson, M.F. Sim, and D.B. Yates, Ger. 30 11 994 A1 (16.10.1980); Chem. Abs., 94 (1981) 83968m.
- [10] M. Szögyi and T. Cserháti, J. Planar Chromatogr., 5, 267 (1992)
- [11] Calculation of the log P indexes was performed by means of the Hansch and Leo method by Professor Roman Kaliszan from The Medical University of Gdańsk, Poland.
- [12] G.L. Biaggi, M.C. Guerra, A.M. Barbaro, and S. Barbieri, J. Chromatogr., 498, 179 (1990)
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BAT3-0026-0062