Quantitative determination of chelidonine in Cynarein tablets by HPLC

• Autorzy: Zagrodzka J. , Gadzikowska M. , Gołkiewicz W. , Cieplucha G. , Grynkiewicz G.
• Języki publikacji: EN

Abstrakty

EN

A variety of HPLC conditions have been studied in the development of a method for selective and accurate determination of chelidonine hydrochloride in tablets of the complex herbal drug CynareinŽ. The result is a simple method based on extraction of chelidonine from tablet material then isocratic reversed-phase chromatography with UV detection. It has been found that chelidonine peak symmetry and tailing, and hence the accuracy of quantification, are highly dependent on the quality of the RP18 stationary phase.

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2000
• Tom: No. 10
• Strony: 122--131
• Opis fizyczny: Bibliogr. 8 poz., rys., tab.

Twórcy

autor

Zagrodzka J.

autor

Gadzikowska M.

autor

Gołkiewicz W.

autor

Cieplucha G.

autor

Grynkiewicz G.

• Pharmaceutical Research Institute, Rydygiera 8, 01-793 Warszawa