Mutagenicity induced in Salmonella strains TA98 and TA100 by diphenylthiophenes

• Autorzy: Budzikur K. A. , Góra M. , Chachaj A. , Mielżyńska-Švach D. , Tejs S. , Łuczyński M. K.
• Języki publikacji: EN

Abstrakty

EN

Mutagenic properties of four different diphenylthiophenes: 3,4-diphenylthiophene, 3,4-di(4'-methylphenyl)thiophene, 3,4-di(4'-methoxyphenyl)thiophene and 3,4-di(4'-pentoxyphenyl)thiophene were investigated applying the Salmonella test. The research was done on two strains of Salmonella Typhimurium: TA98 and TA100, tested in two variants: with (+S9) and without (-S9) enzymatic activation. Only one compound 3,4-di(4'-methylphenyl)thiophene showed mutagenic activity when studied with metabolic activation (+S9) and its mutagenic rate (MR) score was 3.41 for the dose of 10.00µg*plate-1. Other studied compounds did not show any mutagenic activity (+/-S9) and their MR score did not exceed the threshold value of 2.0.

Słowa kluczowe

EN

Ames test; mutation; thiophene monomers

PL

test Amesa; mutacja; monomery tiofenowe

• Wydawca: University of Warmia and Mazury in Olsztyn, Poland
• Czasopismo: Environmental Biotechnology
• Rocznik: 2011
• Tom: Vol. 7, No. 2
• Strony: 65--69
• Opis fizyczny: Bibliogr. 21 poz., tab., wykr.

Twórcy

autor

Budzikur K. A.

autor

Góra M.

autor

Chachaj A.

autor

Mielżyńska-Švach D.

autor

Tejs S.

autor

Łuczyński M. K.

• Department of Environmental Biotechnology, University of Warmia and Mazury in Olsztyn, Sloneczna 45G, 10-718 Olsztyn, Poland,

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