Resorbable multifunctional antibiotic releasing tacks

• Autorzy: Tiainen J. , Knuutila K. , Veiranto M. , Suokas E. , Waris T. , Tormala P. , Kaarela O. , Ashammakhi N.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to compare the pullout forces of recently developed bioabsorbable ciprofloxacin-releasing and plain self-reinforced polylactide/polyglycolide (SR-PLGA) 80/20 tacks in human cadaver parietal bones. Parietal bone pieces (approximately 6 x 20 cm) were collected from five human male cadavers (29-77 years of age). Fifty plain SR-PLGA 80/20 tacks (diameter = 2 mm, length = 6,0 mm) and 50 ciprofloxacin-releasing SR-PLGA 80/20 tacks of similar dimensions were applied to drill holes using a special tack-shooter without tapping the drill holes. The force needed to pull the tacks from human parietal cadaver bones was measured using a universal tensile testing machine. The tack pullout speed was 10 mm/min. Means and standard deviations (SDs) were calculated and analyzed using the Student t test (SPSS version 10.0 for Windows). The pullout forces of the ciprofloxacin-releasing and plain tacks were 147 +/- 10.3 N and 141.4 +/- 12.6 N respectively (insignificant difference, P<0.001). The main cause of failure was the breakage of tack barbs (95% in the both cases). Ciprofloxacin-releasing SR-PLGA tacks have a pullout strength similar to corresponding plain conventional SR-PLGA tacks and they can be applied in cranial bone fixation.

Słowa kluczowe

EN

bioabsorbable; ciprofloxacin; osteofixation; tack

PL

bioabsorpcja

• Wydawca: Polskie Stowarzyszenie Biomateriałów
• Czasopismo: Inżynieria Biomateriałów
• Rocznik: 2004
• Tom: R. 7, nr 38-42
• Strony: 11--11

Twórcy

autor

Tiainen J.

• Department of Surgery, Oulu University Hospital, Oulu, Finland

autor

Knuutila K.

• Institute of Biomaterials, Tampere University of Technology, Tampere, Finland

autor

Veiranto M.

• Institute of Biomaterials, Tampere University of Technology, Tampere, Finland

autor

Suokas E.

• Linvatec Biomaterials Ltd., Tampere, Finland

autor

Waris T.

• Department of Surgery, Oulu University Hospital, Oulu, Finland

autor

Tormala P.

• Institute of Biomaterials, Tampere University of Technology, Tampere, Finland

autor

Kaarela O.

• Department of Surgery, Oulu University Hospital, Oulu, Finland

autor

Ashammakhi N.

• Department of Surgery, Oulu University Hospital, Oulu, Finland