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Pulsed cathodic arc plasma technology deposition of thromboresistant nanostructural carbon coating on components of artificial heart valves

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Języki publikacji
EN
Abstrakty
EN
This paper describes the results of applying of pulsed cathodic-arc plasma (PCAP) method formation in vacuum biocompatible and thromboresistant t-a carbon coatings on the components of artificial heart valves (AHV). The special pulsed arc plasma source was used for evaporation of the graphite cathode to form pulsed accelerated carbon plasma flows and deposited them on polished samples of titanium alloys and components AHV made of the same alloys. Influence of the initial voltage of cathode arc discharge in range of 100-450V and temperature of substrate during the deposition in the range 293-773 degrees of Kelvin on structure, phase composition, hardness and biomedical properties coatings were investigated. The results of investigation of biomedical properties t-a carbon films deposited by PCAP method have shown that the best biocompatibility and thromboresistivity have the nanostructural carbon coatings with cluster size 10-20nm and thickness 0,08-0,1 microns. The artificial heart valves with deposited nanostructural t-a carbon coatings were implanted on ten animals (dogs). The obtained results have shown that the passing of blood through AHV leads to moderate activation of coagulation processes.
Rocznik
Strony
12--16
Opis fizyczny
Bibliogr. 17 poz., rys., tab., wykr.
Twórcy
  • Plasmoteg Sciences Engineering Centre of FTI of National Academy of Sciences of Belarus, 1/3 Kuprevich St., Minsk, 220141, Belarus
Bibliografia
  • [1] Y.P. Ostrovsky., Disk artificial hart valves Planex, J. Engen. Phys. and Thermophys., 69, 3, 478-488 (1996) (in Russian).
  • [2] Gotman, Characteristic of metals used in implant., J. Endourology Dec.11(6), 383-389 (1997).
  • [3] E. Knott, H. Reul, M. Knoch et.al., In vitro comparison of aortic heart valve prostheses, Part 1: Mechanical valves, J. Thorac. Cardiovasc. Surg., 96, 6, 952-961 (1998).
  • [4] H.S. Tran, M.M. Puc, C.W. Hewitt et al., Diamond-like carbon coatings and plasma or glow discharge treatment pf mechanical heart valves, J. Invest. Surg., 12, 133-140 (1999).
  • [5] E.I. Tochitsky, O.G. Sviridovich, N.M. Beliavsky, Deposition of Biocompatible Thromboresistant Coatings from Pulsed Plasma on Artificial Heart Valves, VI Int. Conf. Plasma Physics and Plasma Technol.- Proceedings Book, 2, 471-474, Minsk, Belarus, September 15-19, 2003.
  • [6] Dion, C. Baquery, J.R.Monties, Diamond: the biomaterial of the 21st century, Inter. J. Art. Org., 16, 623-627 (1993).
  • [7] Dion, X.Roques, C. Baquey, et al. Hemocompatibility of diamond-like carbon coating, Biomed. Mater. Eng., 3, 51-55 (1993).
  • [8] L.Lu., M.W. Jones, Diamond-like carbon as biological compatible material for cell culture and medical application, Biomed. Mater. Eng., 3, 223-228 (1993).
  • [9] L Tang, C.Tsai. W.W. Gerberich et al., Biocompatibility of Chemical Vapour Deposited Diamon, Biomaterials, 16, 483-488 (1995).
  • [10] L.A. Thomson, F.C. Law, N. Rusthon, Biocompatibility of diamond-like carbon coating, Biomaterials, 12, 37-40 (1991).
  • [11] M.I.Jones, I.R. McCol, D.M.Grant et al., Hemocompatibility of DLC and TiC-TiN interlayers on titanium, Diamond and Related, 8, 457-462 (1999).
  • [12] E.I. Tochitsky, O.V. Selifanov, V.V.Alylich et al., Electrical Erosion Pulsed Plasma Accelerators for preparing Diamond-like Carbon Coatings, Surf.and Coat. Techn., 47, 522-527 (1991).
  • [13] E.I. Tochitsky, A.V. Stanishevskii, I.A. Kapustin, et al., Structure and properties of carbon films prepared by pulsed vacuum arc deposition, Surf. And Coat. Techn., 47, 292-298 (1991).
  • [14] A.V. Stanishevsky, E.I. Tochitsky, Formation of Metastable Carbon Film Structure by pulsed Arc Plasma deposition in Vacuum, J of Chemical Vapor Depos., 4, 297-310 (1996).
  • [15] T.L. Parker, K.L. Parker, I.R. McColl et al., The biocompatibility of low temperature diamond-like carbon films: transmission electron microscopy and cytotoxicity study, Diamond and Related Mater., 3, 1120-1123 (1994).
  • [16] Y.X. Leng, J.Y. Chen, P. Yang et al., Mechanical properties and platelet adhesion behavior of diamond-like carbon films synthesis by pulsed vacuum arc plasma deposition, Surface Science, 531, 177-184 (2003).
  • [17] S.I. Korsak, Thromnogenous artificial valves Planex of dependence from type of surface coating. Zdravookhranenie, 8, 14-18 (1997) (in Russian).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-AGH5-0008-0070
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