Should the Lopot-plot be used in daily practice to optimise hemodialysis treatment?

• Autorzy: Korohoda P. , Sypka P. , Pietrzyk J. A.
• Języki publikacji: EN

Abstrakty

EN

The paper presents an application of the Lopot-plot, which compares the time-averaged concentration (TAC) and the time-averaged deviation (TAD) of the weekly dialysis cycle, to comprise the results of intensive computational study. The presented case is based on 420 one-week-cycle simulations to verify the consequences implied by the change of the treatments schedule from nonuniformly to uniformly distributed over the week. The concept of steady state is explained and utilized to obtain periodical runs of the urea concentration. The presented graphs encouragingly indicate the potential of such plots in presenting results of multivariable intensive computations that should be advisably performed during the planning process of hemodialysis treatment.

Słowa kluczowe

EN

intermittent hemodialysis; hemodialisys modelling; hemodialysis adequacy; Lopot-plots

• Wydawca: Uniwersytet Jagielloński - Collegium Medicum ; Index Copernicus Sp. z o.o.
• Czasopismo: Bio-Algorithms and Med-Systems
• Rocznik: 2012
• Tom: Vol. 8, no. 4
• Strony: 417--423
• Opis fizyczny: Bibliogr. 8 poz., rys., tab., wykr.

Twórcy

autor

Korohoda P.

• AGH University of Science and Technology, Department of Electronics Mickiewicza 30 av., 30-059 Kraków, Poland

autor

Sypka P.

• AGH University of Science and Technology, Department of Electronics Mickiewicza 30 av., 30-059 Kraków, Poland

autor

Pietrzyk J. A.

• Department of Paediatric Nephrology, University Children’s Hospital of Cracow, 256 Wielicka str., 30-663 Kraków, Poland,

Bibliografia

• 1. Sargent J. A., Gotch F. A. (1980). Mathematical modelling of dialysis therapy. Kidney International, 18: (Suppl 10): 2-10.
• 2. Depner T.A. (1997). Prescribing Hemodialysis: A Guide to Urea Modeling. Kluwer Academic Publishers, 6th print.
• 3. Casino F.G., Lopez T. (1996). The equivalent renal urea clearance: a new parameter to assess dialysis dose. Nephrology Dialysis Transplantation, 11: 1574–1581.
• 4. Gotch F.A. (1998). The current place of urea kinetic modelling with respect to different dialysis modalities. Nephrology Dialysis Transplantation, 13: 10–14.
• 5. Lopot F., Valek A. (1988). Time averaged concentration – time averaged deviation: a new concept in mathematical assessment of dialysis adequacy. Nephrology Dialysis Transplantation, 3(6): 846–848.
• 6. Lopot F., Valek A. (1998). Quantification of dialysis unphysiology. Nephrology Dialysis Transplantation, 13: 74–78.
• 7. Daugirdas J.T., Tattersall J. (2010). Effect of treatment spacing and frequency on three measures of equivalent clearance, including standard Kt/V. Nephrology Dialysis Transplantation, 25: 558–561.
• 8. Korohoda P., Pietrzyk J.A., Schneditz D. (2010). Quantifying the discontinuity of haemodialysis dose with time-averaged concentration (TAC) and time-averaged deviation (TAD). Nephrology Dialysis Transplantation, 25(3): 1011–1012.