Disruptions in brain functional connectivity: The hidden risk for oxygen-intolerant professional divers in simulated deep water

• Autorzy: Formaggio Emanuela , Pastena Lucio , Melucci Massimo , Ricciardi Lucio , Storti Silvia Francesca

Identyfikatory

DOI

10.1016/j.bbe.2024.01.004

• Języki publikacji: EN

Abstrakty

EN

In this study, we investigated the effects of oxygen toxicity on brain activity and functional connectivity (FC) in divers using a closed-circuit oxygen breathing apparatus. We acquired and analyzed electroencephalographic (EEG) signals from a group of normal professional divers (PD) and a group that developed oxygen intolerance, i.e., oxygen-intolerant professional divers (OPD), to evaluate the potential risk of a dive and understand the physiological mechanisms involved. The results highlighted a significant difference in the baseline levels of α rhythm between PD and OPD, with PD exhibiting a lower level to counteract the effects of increased O₂ inhalation, while OPD showed a higher level that resulted in a pathological state. Connectivity analysis revealed a strong correlation between cognitive and motor regions, and high levels of α synchronization at rest in OPDs. Our findings suggest that a pathological condition may underlie the higher α levels observed in these individuals when facing the stress of high O₂ inhalation. These findings support the hypothesis that oxygen modulates brain networks, and have important implications for understanding the neural mechanisms involved in oxygen toxicity. The study also provides a unique opportunity to investigate the impact of neurophysiological activity in simulated critical scenarios, and opens up new perspectives in the screening and monitoring of divers.

Słowa kluczowe

EN

EEG signal; functional connectivity; hyperbaric oxygen; hyperbaric chamber; source analysis

PL

sygnał EEG; tlen hiperbaryczny; komora hiperbaryczna

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2024
• Tom: Vol. 44, no. 1
• Strony: 209--217
• Opis fizyczny: Bibliogr. 49 poz., rys.

Twórcy

autor

Formaggio Emanuela

• Department of Neuroscience, Section of Rehabilitation, University of Padova, Italy

autor

Pastena Lucio

• Department of Neurological Sciences, University of Rome, La Sapienza, Italy

autor

Melucci Massimo

• Italian Navy Medical Service Comsubin Varignano, Le Grazie (La Spezia), Italy

autor

Ricciardi Lucio

• Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Italy

autor

Storti Silvia Francesca

• Department of Engineering for Innovation Medicine, University of Verona, Italy

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Uwagi

PL

Opracowanie rekordu ze środków MNiSW, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2024).