Emulsions as vehicles for the controlled release of astaxanthin in topical application

• Autorzy: Dymek Michał , Sikora Elżbieta

Identyfikatory

DOI

10.24425/cpe.2021.138939

• Języki publikacji: EN

Abstrakty

EN

In the work, the antioxidant activity of astaxanthin (AST) and the influence of the base formulation on the kinetics of AST release were studied. Three stable O/W AST-loaded emulsions, differing in droplet size (12.7 m(E1), 3.8 m(E2), 3.2 m(E3)) and a nanoemulsion (0.13 m, NE) were prepared. The results confirmed very strong antioxidant activity of AST. The emulsion internal phase droplet size did not significantly affect the AST release. The amount of released AST was respectively: 13.60% (E1), 11.42% (E2), 9.45% (E3), 9.71% (NE). The best fit to experimental data was obtained using the Higuchi model for emulsions and the Korsmeyer-Peppas model for NE. The results show that the AST release process is limited by the diffusion through carriers and the prepared O/W emulsions can be applied as vehicles for delivery of astaxanthin to the skin, ensuring effective anti-aging action of the cosmetics.

Słowa kluczowe

EN

astaxanthin; release kinetics; skin delivery systems; emulsions; antioxidant activity

PL

astaksantyna; kinetyka uwalniania; emulsja; aktywność antyoksydacyjna

• Wydawca: Komitet Inżynierii Chemicznej i Procesowej Polskiej Akademii Nauk
• Czasopismo: Chemical and Process Engineering
• Rocznik: 2021
• Tom: Vol. 42, nr 4
• Strony: 439--–450
• Opis fizyczny: Bibliogr. 37 poz., tab., rys.

Twórcy

autor

Dymek Michał

• Cracow University of Technology, Faculty of Chemical Engineering and Technology, Warszawska 24, 31-155 Kraków, Poland

autor

Sikora Elżbieta

• Cracow University of Technology, Faculty of Chemical Engineering and Technology, Warszawska 24, 31-155 Kraków, Poland

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