The assessment of consecutive 4D-CT scans during simulation for lung stereotactic body radiation therapy patients

• Autorzy: Savanovic Milovan , Strbac Bojan , Jaros Drazan , Foulquier Jean-Noel

Identyfikatory

DOI

10.2478/pjmpe-2020-0023

• Języki publikacji: EN

Abstrakty

EN

Purpose: To evaluate the breathing amplitude, tumor motion, patient positioning, and treatment volumes among consecutive four-dimensional computed tomography (4D-CT) scans, during the simulation for lung stereotactic body radiation therapy (SBRT). Material and methods: The variation and shape of the breathing amplitude, patient positioning, and treatment volumes were evaluated for 55 lung cancer patients after consecutive 4D-CT acquisitions, scanned at one-week intervals. The impact of variation in the breathing amplitude on lung tumor motion was determined for 20 patients. The gross tumor volume (GTV) was contoured from a free-breathing CT scan and at ten phases of the respiratory cycle, for both 4D-CTs (440 phases in total). Results: Breathing amplitude decreased by 3.6 (3.4-4.9) mm, tumor motion by 3.2 (0.4-5.0) mm while breathing period increased by 4 (2-6) s, inter-scan for 20 patients. Intra-scan variation was 4 times greater for the breathing amplitude, 5 times for the breathing period, and 8 times for the breathing cycle, comparing irregular versus regular breathing patterns for 55 patients. Using coaching, the breathing amplitude increases 3 to 8 mm, and the breathing period 2 to 6 s. Differences in the contoured treatment volumes were less than 10% between consecutive scans. Patient positioning remained stable, with a small inter-scan difference of 1.1 (0.6-1.4) mm. Conclusion: Decreasing the inter-scan breathing amplitude decreases the tumor motion reciprocally. When the breathing amplitude decreases, the breathing period increases at inter- and intra-scan, especially during irregular breathing. Coaching improves respiration, keeping the initial shape of the breathing amplitude. Contoured treatment volumes and patient positioning were reproducible through successive scans.

Słowa kluczowe

EN

lung cancer; breathing amplitude; tumor motion; 4D-CT; SBRT

• Wydawca: Polskie Towarzystwo Fizyki Medycznej ; De Gruyter
• Czasopismo: Polish Journal of Medical Physics and Engineering
• Rocznik: 2020
• Tom: Vol. 26, Iss. 4
• Strony: 193--199
• Opis fizyczny: Bibliogr. 22 poz., rys., tab.

Twórcy

autor

Savanovic Milovan

• Department of Radiation Oncology, Tenon Hospital, 75020 Paris, France
• Faculty of Medicine, University of Paris-Saclay, 94276 Le Kremlin-Bicêtre, France

autor

Strbac Bojan

• MATER Private Hospital, Physics department, Eccles Street, Dublin 7, Ireland

autor

Jaros Drazan

• Affidea, International Medical Centers, Center for Radiotherapy, 78000 Banja Luka, Bosnia, and Herzegovina

autor

Foulquier Jean-Noel

• Department of Radiation Oncology, Tenon Hospital, 75020 Paris, France

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).