Two-stage bacteriophage production process supported by the electromagnetic field

• Autorzy: Rakoczy Rafał , Konopacki Maciej , Kordas Marian , Grygorcewicz Bartłomiej

Identyfikatory

DOI

10.24425/cpe.2022.142289

• Języki publikacji: EN

Abstrakty

EN

The practical applications of bacteriophages are associated with the problems related to the intensification, optimization of process production of this biomaterial and the search for new methods of production. The production of bacteriophages requires a fine balance between the dynamic growth of the bacteriophage and the host. The electromagnetic field (EMF) is a promising biotechnological method for the process production of bacteriophages. This study evaluates the use of various types of EMF to enhance the process. It was found that the process production of bacteriophages is divided into two stages. In the first stage, the influence of various types of EMF on the proliferation process of bacteria (host) was analyzed. Secondly, the process production of bacteriophage was implemented for the optimal infection conditions under the action of the various types of EMF. Moreover, the study demonstrated that the most effective bacteriophage production was the process with the application of the rotating magnetic field (RMF), pulsed magnetic field (PMF) and the static magnetic field (SMF) with negative polarity.

Słowa kluczowe

EN

bioreactor; biotechnology; bacteriophage production; electromagnetic field

PL

bioreaktor; biotechnologia; produkcja bakteriofagów; pole elektromagnetyczne

• Wydawca: Komitet Inżynierii Chemicznej i Procesowej Polskiej Akademii Nauk
• Czasopismo: Chemical and Process Engineering
• Rocznik: 2022
• Tom: Vol. 43, nr 4
• Strony: 491--–506
• Opis fizyczny: Bibliogr. 50 poz., tab., rys., wykr.

Twórcy

autor

Rakoczy Rafał

• West Pomeranian University of Technology in Szczecin, Faculty of Chemical Technology and Engineering, Department of Chemical and Process Engineering, al. Piastów 42, 71-065 Szczecin, Poland

• https://orcid.org/0000-0002-5770-926X

autor

Konopacki Maciej

• West Pomeranian University of Technology in Szczecin, Faculty of Chemical Technology and Engineering, Department of Chemical and Process Engineering, al. Piastów 42, 71-065 Szczecin, Poland
• Pomeranian Medical University in Szczecin, Chair of Microbiology, Immunology and Laboratory Medicine, Department of Laboratory Medicine, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland

• https://orcid.org/0000-0002-2240-7317

autor

Kordas Marian

• West Pomeranian University of Technology in Szczecin, Faculty of Chemical Technology and Engineering, Department of Chemical and Process Engineering, al. Piastów 42, 71-065 Szczecin, Poland

• https://orcid.org/0000-0001-9982-1658

autor

Grygorcewicz Bartłomiej

• Pomeranian Medical University in Szczecin, Chair of Microbiology, Immunology and Laboratory Medicine, Department of Laboratory Medicine, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland

• https://orcid.org/0000-0002-0593-0069

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