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Analysis and development of the adhesion of stent coatings

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The influence of the surface roughness on adhesion strength of polyurethane coating on stainless steel alloy (316LVM) is introduced. These coatings are one of the development directions in coronary stent production. One of the widely spread stent base material is the 316LVM, so in the presented study these materials were involved. The samples were prepared by etching and electro-polishing. The current density and polishing time were changed to create samples with different surface roughness. After electro-polishing polyurethane (Chronoflex®) coating was applied. The adhesion of the coating on different surfaces was tested by scratch test (nano indenter technique). The increasing surface roughness gives stronger adhesion. According to our experiments it was concluded that the coronary stents, treated by etching without polishing could cut out the balloons during expansion, therefore the surface roughness should be under this value. It is recommended to use an electro-chemical treatment that is resulting Ra=1.5-2.0 μm roughness.
Twórcy
autor
  • Department of Materials Science and Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, Hungary
autor
  • Department of Vehicle Manufacturing and Repairing, Faculty of Transportation Engineering and Vehicle Engineering, Budapest University of Technology and Economics, Budapest, Hungary
autor
  • Department of Materials Science and Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, Hungary
autor
  • Department of Materials Science and Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, Hungary
autor
  • Department of Materials Science and Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, Hungary
Bibliografia
  • 1. Tayapiwatna C.: Multidisciplinary research and development: The biomedical engineering approach. “Maejo International Journal of Science and Technology” 2007, Vol. 01, pp. 98 – 99.
  • 2. Hara H., et al.: Role of stent design and coatings on restenosis and thrombosis. “Advanced Drug Delivery Reviews” 2006, Vol. 58, pp. 377 – 386.
  • 3. Martin D.M., Boyle F.J.: Drug-eluting stents for coronary artery disease: A review. “Medical Engineering & Physics” 2011, Vol. 33, pp. 148 – 163.
  • 4. Gallino E., et al.: Plasma polymerized allylamine films deposited on 316L stainless steel for cardiovascular stent coatings. “Surface and Coatings Technology” 2010, Vol. 205, pp. 2461 – 2468.
  • 5. Palmaz J.C., et al.: Influence of stent design and material composition on procedure outcome. “Journal of Vascular Surgery” 2002, Vol. 36, pp. 1031 – 1039.
  • 6. Bakhshi R., et al.: Polymeric coating of surface modified nitinol stent with POSSnanocomposite polymer. “Colloid Surfaces B” 2011, Vol. 86, pp. 93 – 105.
  • 7. Unger F., et al.: Poly(ethylene carbonate): A thermoelastic and biodegradable biomaterial for drug eluting stent coatings?. “Journal of Controlled Release” 2007, Vol. 117, pp. 312 – 321.
  • 8. Crowder S.W., et al.: Modular polymer design to regulate phenotype and oxidative response of human coronary artery cells for potential stent coating applications. “Acta Biomaterialia” 2012, Vol. 8, pp. 559 – 569.
  • 9. Mani G., et al.: Coronary stents: A materials perspective. “Biomaterials” 2007, Vol. 28, pp.1689 – 1710.
  • 10. Shan W.L., et al.: Adhesion and cohesion in structures containing suspended microscopic polymeric films. “Acta Biomaterialia” 2012, Vol. 8, pp. 1469 – 1480.
  • 11. Lewis F., et al.: Study of the adhesion of thin plasma fluorocarbon coatings resisting plastic deformation for stent applications. “Journal of Applied Physics” 2008, Vol. 41, pp. 045310 – 045400.
  • 12. Bian H., et al.: In vitro study of poly(ethylene carbonate) as a drug-eluting stent coating. “Progress in Natural Science: Materials International” 2012, Vol. 22, pp. 295 – 302.
  • 13. CSM Instruments: Advanced Mechanical Surface Testing. In: CSM Instruments application note, Peseux, Switzerland, 2006.
  • 14. Bull S.J., Berasetegui E.G.: An overview of the potential of quantitative coating adhesion measurement by scratch testing. “Tribology International” 2006, Vol. 39, pp. 99 – 114.
  • 15. Vodnick D., Nay R.: Interfacial Adhesion of Viscoelastic Coatings on Medical Stents. Hysitron application note, Hysitron, Eden Prairie, MN, USA, 2011.
  • 16. Barnes D., Johnson S., Snell R., Best S.: Using scratch testing to measure the adhesion strength of calcium phosphate coatings applied to poly(carbonate-urethane) substrates. “Biomedical Materials” 2012, Vol. 6, pp. 128 – 138.
  • 17. Ichimura H., Ishii Y.: Effects of indenter radius on the critical load in scratch testing. “Surface and Coatings Technology” 2003, Vol. 165, pp. 1 – 7.
  • 18. Randall N.X. et al.: The effect of intrinsic parameters on the critical load as measured with the scratch test method. “Surface and Coatings Technology” 2001, Vol. 137, pp. 146 –151.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-a69f3c58-01b7-4eec-a85c-5b6bfa7dba08
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