Developing a Model of Peripheral Nerve Graft Based on Natural Polymers

• Autorzy: Kucharska M. , Niekraszewicz A. , Kardas I. , Marcol W. , Larysz-Brysz M , Lewin-Kowalik J.

Warianty tytułu

PL

Opracowanie modelu protezy nerwu obwodowego z polimeru naturalnego

• Języki publikacji: EN

Abstrakty

EN

Presented are the results of investigations into the preparation of a peripheral nerve prosthesis. The prosthesis is built up of a multichannel core having a diameter of 2 to 5 mm. The core prepared by freeze drying is housed in a polymeric sleeve. The prosthesis core is made of microcrystalline chitosan (MCCh) while the sleeve is prepared from poly(DL-lactide-coglycolide) copolymer. The usefulness of the prepared biomaterial was assessed by in vivo testing on animals.

PL

W pracy przedstawiono badania prowadzące do opracowania modelu protezy nerwu obwodowego. Proteza zbudowana jest z wielokanałowego rdzenia o średnicy od 2 do 5 mm wytworzonego metodą liofilizacji i osadzonego w tulei polimerowej. Rdzeń protezy wytworzono z mikrokrystalicznego chitozanu (MKCh), natomiast tuleję stanowi błona uzyskana z resorbowalnego kopolimeru poli(DL-laktyd-ko-glikolid). Opracowany biomateriał poddano ocenie przydatności w warunkach in vivo z wykorzystaniem zwierząt.

Słowa kluczowe

EN

biopolymers; peripheral nerve; prosthesis; chitosan

PL

biopolimery; protezy nerwów obwodowych; chitozan

• Wydawca: Sieć Badawcza Łukasiewicz - Łódzki Instytut Technologiczny
• Czasopismo: Fibres & Textiles in Eastern Europe
• Rocznik: 2012
• Tom: Vol. 20, no. 6B (96)
• Strony: 115--120
• Opis fizyczny: Bibliogr. 23 poz., rys., tab., wykr.

Twórcy

autor

Kucharska M.

• Poland, Łódź, Institute of Biopolymers and Chemical Fibres
• [e-mail]

autor

Niekraszewicz A.

• Poland, Łódź, Institute of Biopolymers and Chemical Fibres

autor

Kardas I.

• Poland, Łódź, Institute of Biopolymers and Chemical Fibres

autor

Marcol W.

• Poland, Katowice, Medical University of Silesia, Department of Physiology

autor

Larysz-Brysz M

• Poland, Katowice, Medical University of Silesia, Department of Physiology

autor

Lewin-Kowalik J.

• Poland, Katowice, Medical University of Silesia, Department of Physiology

Bibliografia

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