Effect of microwave power on EPR spectra of DOPA-melanin-netilmicin complexes with different drug concentrations : a study at temperatures in the range of 125-275 K

• Autorzy: Zdybel M. , Pilawa B. , Buszman E. , Wrześniok D. , Krzyminiewski R. , Kruczyński Z.
• Konferencja: Electron Magnetic Resonance Forum EMR-PL (2; 16-18.05.2013; Częstochowa-Hucisko, Poland )
• Języki publikacji: EN

Abstrakty

EN

Electron paramagnetic resonance (EPR) spectra of the model eumelanin – DOPA-melanin complexes with netilmicin measured with a microwave power in the range 0.3–200 mW were examined. The influence of microwave power on amplitudes (A) and linewidths (ΔBpp) of the spectra was determined. The EPR spectra were recorded by a BRUKER spectrometer at temperatures 125, 175, 225 and 275 K. Continuous microwave saturation of EPR lines was used to compare the acceleration of spin-lattice relaxation processes in melanin samples. Changes of the parameters of the EPR spectra of DOPA-melanin-netilmicin complexes, with the microwave power for the samples differing in netilmicin concentrations, were observed. The effect of temperature on the changes of the EPR spectra of the analyzed melanin complexes with the microwave power was determined. The spin-lattice relaxation is faster at higher temperatures for all the tested melanin complexes.

Słowa kluczowe

EN

DOPA-melanin; electron paramagnetic resonance (EPR) spectroscopy; free radicals; netilmicin

• Wydawca: Institute of Nuclear Chemistry and Technology
• Czasopismo: Nukleonika
• Rocznik: 2013
• Tom: Vol. 58, No. 3
• Strony: 407--411
• Opis fizyczny: Bibliogr. 33 poz., rys.

Twórcy

autor

Zdybel M.

• Department of Biophysics, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia in Katowice, 8 Jedności Str., 41-200 Sosnowiec, Poland, Tel.: [phone], Fax: [phone]

autor

Pilawa B.

• Department of Biophysics, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia in Katowice, 8 Jedności Str., 41-200 Sosnowiec, Poland, Tel.: [phone], Fax: [phone]

autor

Buszman E.

• Department of Pharmaceutical Chemistry, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia in Katowice, 4 Jagiellońska Str., 41-200 Sosnowiec, Poland

autor

Wrześniok D.

• Department of Pharmaceutical Chemistry, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia in Katowice, 4 Jagiellońska Str., 41-200 Sosnowiec, Poland

autor

Krzyminiewski R.

• Department of Medical Physics, Institute of Physics, Adam Mickiewicz University, 85 Umultowska Str., 61-614 Poznań, Poland

autor

Kruczyński Z.

• Department of Medical Physics, Institute of Physics, Adam Mickiewicz University, 85 Umultowska Str., 61-614 Poznań, Poland

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