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A series of 2,4-dimethoxy phenyl chalcones have been synthesized by Crossed-Aldol condensation of 2,4-dimethoxy phenyl and various substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.
Rocznik
Tom
Strony
48--65
Opis fizyczny
Bibliogr. 44 poz., ryc., rys., tab.
Twórcy
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram - 608102, India.
autor
- Department of Chemistry, Annamalai University, Annamalainagar - 608002, India.
Bibliografia
- [1] Thirunarayanan G., Vanangamudi G., Subramanian M., Organic Chem: An Indian J. 9(1) (2013) 1-16.
- [2] Janaki P., Sekar K. G., Thirunarayanan G., J. Saudi Chem. Soc. 2013, Accepted and in press. DOI: org/10.1016/j.jscs.2012.11.013.
- [3] Holla B. S., Akberali P. M., Shivananda M. K., IL Farmaco 55 (2000) 256-261.
- [4] Venkat Reddy G., Maitraie D., Narsaiah B., Rambabu Y., ShanthanRao P., Synth. Commun 31(18) (2004) 2882-2884.
- [5] Orsini F., Sello G., Fumagalli T., Synlett. (2006), 1717-1718.
- [6] Vanangamudi G., Subramanian S., Jayanthi P., Arulkumaran R., Kamalakkannan D., Thirunarayanan G., Arab. J. Chem., 201, DOI: 10.1016/j.arabjc.2010.07.019.
- [7] Tran T. D., Park H., Ecker G. F., Thai K. M., 2,3’-Hydroxychalcone Analogues: Synthesis and Structure-PGE2 Inhibitory Activity Relationship, 12th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-12) 1-30 November 2008; http://www.usc.es/congresos/ecsoc/12/ECSOC12.htm &http://www.mdpi.org/ecsoc-12 No. C0011, pp 1-7.
- [8] Mohan S. B., Behera T. P., Ravi Kumar B. V. V., Int. J. ChemTech. Res. 2(3) 2010 1634-1637.
- [9] Thirunarayanan G., Vanangamudi G., Arkivoc. 12 (2006) 58-64.
- [10] Thirunarayanan G., Ananthakrishna Nadar P., J. Indian Chem. Soc. 83(11) (2006) 1107-1112.
- [11] Ballini R., Bosica G., Maggi R., Ricciutelli M., Righi P., Sartori G., Sartorio R., Green Chem. 3 (2001) 178-180.
- [12] Solhy A., Tahir R., Sebti S. Skouta R., Bousmina M., Zahouily M., Larzek M., Appl. Catal. A: General. 374 (2010) 189-193.
- [13] Thirunarayanan G., J. Indian Chem. Soc. 84 (2008) 447-451.
- [14] Basaif S. A., Sobahi T. R., Khalil A. K., Hassan M. A., Bulletin of the Korean Chem. Soc. 26(11) (2005) 1677-1681.
- [15] Xu Q., Yang Z., Yin D., Zhang F., Catal. Commun. 9(1) (2008) 1579-1582.
- [16] Kumar P., Kumar S., Husain K., Kumar A., Bioorg. Med. Chem. 18(14) (2010) 4965-4974.
- [17] Zhang Z., Dong Y., W., Wang G. W., Chem. Lett. 32(10) (2003) 966-967.
- [18] Thirunarayanan G., IUP. J. Chem. 3(4) (2010) 35-54.
- [19] Thirunarayanan G., et al., Elixir Org. Chem. 45 (2012) 7898-7905.
- [20] Thirunarayanan G., Mayavel P., Thirumurthy K., Spectrochimica Acta. 91A (2012) 18-22.
- [21] Sundararajan R., et al., Int. J. Pharm. Chem. Sci. 1(4) (2012) 1657-1677.
- [22] Thirunarayanan G., Surya S., Srinivasan S., Vanangamudi G., Sathiyendiran V., Spectrochim. Acta. 75A (2010) 152-156.
- [23] Janaki P., Sekar K. G., Thirunarayanan G., Org. Chem: An Indian J. 9(2) (2013) 68-80.
- [24] Arulkumaran R., Vijayakumar S., Sundararajan R., Sakthinathan S. P., Kamalakkannan D., Suresh R., Ranganathan K., Vanangamudi G., Thirunarayanan G., International Letters of Chemistry, Physics and Astronomy 4 (2012) 17-38.
- [25] Kamalakkannan D, Vanangamudi G, Arulkumaran R, Thirumurthy K, Mayavel P, Thirunarayanan G, Elixir Org. Chem., 46, 2012, 8157-8166.
- [26] Sivakumar M., PhrabuSreeneivasan S., Kumar V., Doble M., Bioorg. Med Chem. Lett. 17(10) (2007) 3169-3172.
- [27] Liu X., Go M. L., Bioorg. Med.Chem. 14(1) (2006) 153-163.
- [28] Arulkumaran R, et al., IUP J. Chem. 3(1) (2010) 82-98.
- [29] Deng J., Sanchez T., Lalith Q. A. M., Bioorg. Med. Chem. 15(14) (2007) 4985-5002.
- [30] Bauer A. W., Kirby W. M. M., Sherris J. C., Truck M., Am. J. Clin. Pathol. 45 (1966) 493-496.
- [31] Thirunarayanan G., “Fly-ash: H2O Assisted Aldol Condensation: Effect of Solvents on the Synthesis of Some Aryl (E) 2-propen-1-ones” Accepted article in Annales, UMCS Chem. J., 2013.
- [32] Marquardt F. H., Helv. Chim. Acta. 48 (7) (1965) 1476-1485.
- [33] Liu Xiaoling, Bioorg. Med. Chem. 14(1) (2006) 153-163.
- [34] Buu-Hoi Ng. Ph., J. Org. Chem. 22 (1957) 193-7. [35] Vandrewala H. P., J. Univ. Bom Sci: Phys Sci, Math, Biol. Sci. Med. 16 (1948) 43-5.
- [36] Kauffmann Hugo, Ber. Dtsch. Chem. Ges. 54B (1921) 795-802.
- [37] Swain C. G., Lupton Jr. E. C., J. Am. Chem. Soc. 90(16) (1968) 4328-4337.
- [38] Deiva C. M., Pappano N. B., Debattisata N. B., Rev. Microbiol. 29(4) (1998) 307-310.
- [39] Thirunarayanan G., J. Saudi Chem. Soc., 2011. DOI:10.1016/j.jscs.2011.12.003.
- [40] K. Ranganathan, R. Suresh, D. Kamalakkannan, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, S. Vijayakumar, G. Vanangamudi, K. Thirumurthy, P. Mayavel, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 4 (2012) 66-75.
- [41] R. Arulkumaran, S. Vijayakumar, R. Sundararajan, S. P. Sakthinathan, D. Kamalakkannan, R. Suresh, K. Ranganathan, P. R. Rajakumar, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 5 (2013) 21-38.
- [42] S. Vijayakumar, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, R. Suresh, D. Kamalakkannan, K. Ranganathan, K. Sathiyamoorthy, V. Mala, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 9(1) (2013) 68-86.
- [43] Thirunarayanan G., Sekar K. G., International Letters of Chemistry, Physics and Astronomy 10 (2013) 18-34.
- [44] R. Sundararajan, R. Arulkumaran, S. Vijayakumar, D. Kamalakkannan, R. Suresh, S. John Joseph, K. Ranganathan, S. P. Sakthinathan, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 1 (2014) 67-73.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-9e6cc1b8-9638-481a-aa3e-6cca853ccf90