Encapsulation of l-menthol in hydroxypropyl-β-cyclodextrin and release characteristics of the inclusion complex

• Autorzy: Zhu G. , Xiao Z. , Zhu G. , Zhou R. , Niu Y.

Identyfikatory

DOI

10.1515/pjct-2016-0056

• Języki publikacji: EN

Abstrakty

EN

l-menthol has been widely used in flavour, food and pharmaceuticals. Because of its high volatility and whisker growth, l-menthol-hydroxypropyl-β-cyclodextrin inclusion complex was produced to improve shelf-life, provide protection, and enhance the stability of l-menthol. The inclusion complex was characterized by Fourier transform infrared spectroscopy, X-ray diffraction. The results show that l-menthol was successfully encapsulated in hydroxypropyl-β-cyclodextrin. l-menthol loading capacity is about 8.44%. Geometries and binding energies of l-menthol-hydroxypropyl-β-cyclodextrin inclusion complexes were investigated using molecular mechanics calculations. The shape and orientation of the most stable complex, and the minimum binding energy were determined. L-menthol release from complex was determined by thermogravimetric analysis. Two l-menthol release rate peaks were observed at 69.3 and 279.1°C. The l-menthol release reaction order, release activation energy and the preexponential factor were obtained.

Słowa kluczowe

EN

l-menthol; inclusion complex; release characteristics; binding energy; release kinetics

• Wydawca: West Pomeranian University of Technology. Publishing House
• Czasopismo: Polish Journal of Chemical Technology
• Rocznik: 2016
• Tom: Vol. 18, nr 3
• Strony: 110--116
• Opis fizyczny: Bibliogr. 25 poz., rys., tab.

Twórcy

autor

Zhu G.

• Shanghai Institute of Technology, No. 100 Haiquan Road, Shanghai, 201418, PR China

autor

Xiao Z.

• Shanghai Institute of Technology, No. 100 Haiquan Road, Shanghai, 201418, PR China

autor

Zhu G.

• 14846, 43 Ave. Edmonton, Alberta, T6H 5S1, Canada

autor

Zhou R.

• Shanghai Institute of Technology, No. 100 Haiquan Road, Shanghai, 201418, PR China

autor

Niu Y.

• Shanghai Institute of Technology, No. 100 Haiquan Road, Shanghai, 201418, PR China

Bibliografia

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Uwagi

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę.

Autor Zhou R. w artykule jest błędnie wpisany - Rujunzhou.