Application of therapeutic linear accelerators for the production of radioisotopes used in nuclear medicine

• Autorzy: Konefał Adam , Orlef Andrzej , Sokół Maria

Identyfikatory

DOI

10.2478/pjmpe-2022-0013

• Języki publikacji: EN

Abstrakty

EN

This review paper summarizes the possibilities of the use of therapeutic linear electron accelerators for the production of radioisotopes for nuclear medicine. This work is based on our published results and the thematically similar papers by other authors, directly related to five medical radioisotopes as ^99Mo/99mTc, ¹⁹⁸Au, ¹⁸⁶Re, ¹⁸⁸Re, ^117mSn, produced using therapeutic linacs. Our unpublished data relating to the issues discussed have also been used here. In the experiments, two types of radiation were included in the analysis of the radioisotope production process, i.e. the therapeutic twenty-megavolt (20 MV) X-rays generated by Varian linacs and neutron radiation contaminating the therapeutic beam. Thus, the debated radioisotopes are produced in the photonuclear reactions and in the neutron ones. Linear therapeutic accelerators do not allow the production of radioisotopes with high specific activities, but the massive targets can be used instead. Thus, the amount of the produced radioisotopes may be increased. Apart from linear accelerators, more and more often, the production of radioisotopes is carried out in small medical cyclotrons. More such cyclotrons are developed, built, and sold commercially than for scientific research. The radioisotopes produced with the use of therapeutic linacs or cyclotrons can be successfully applied in various laboratory tests and in research.

Słowa kluczowe

EN

nuclear medicine; radioisotopes; therapeutic linacs

• Wydawca: Polskie Towarzystwo Fizyki Medycznej ; De Gruyter
• Czasopismo: Polish Journal of Medical Physics and Engineering
• Rocznik: 2022
• Tom: Vol. 28, Iss. 3
• Strony: 107--116
• Opis fizyczny: Bibliogr. 52 poz., rys., tab.

Twórcy

autor

Konefał Adam

• Institute of Physics, University of Silesia in Katowice, Poland

autor

Orlef Andrzej

• Department of Medical Physics, Maria Sklodowska-Curie National Research Institute of Oncology, Poland

autor

Sokół Maria

• Department of Medical Physics, Maria Sklodowska-Curie National Research Institute of Oncology, Poland

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Uwagi

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).