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RP-HPLC analysis of withanolides in the flowers, leaves, and roots of Withania somnifera

Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Ashwaghanda, Withania somnifera , is one of the most widely used herbs in Ayurvedic medicine. Leaves and roots are the traditionally used parts of the plant. An RP-HPLC method using a binary acetonitrile-water gradient containing 0.1% acetic acid has been developed for analysis of withaferin A. The method was validated in accordance with ICH guidelines and used for analysis of the withanolide content of the flowers, leaves, and roots of W. somnifera . The withanolide content was highest in the flowers.
Słowa kluczowe
Rocznik
Strony
473--480
Opis fizyczny
Bibliogr. 13 poz., rys., tab.
Twórcy
autor
  • University of Beni-Sueif Faculty of Pharmacy Beni-Sueif Egypt
autor
  • University of Beni-Sueif Faculty of Pharmacy Beni-Sueif Egypt
autor
  • University of Karachi H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences Karachi Pakistan
autor
  • University of Karachi H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences Karachi Pakistan
autor
  • University of Karachi H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences Karachi Pakistan
  • University of Karachi H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences Karachi Pakistan
Bibliografia
  • [1] R. Schliebs, S.K. Liebmann, A. Kumar, S. Ghosal, and V. Bigl, Neurochem. Int. 30 , 181 (1973)
  • [2] A.B. Ray and M. Gupta, Prog. Chem. Org. Nat. Prod., 63 , 2 (1994)
  • [3] S.K. Bhattacharya, K.S. Satyan, and S. Ghosal, Indian J. Exp. Biol., 35 , 236 (1997)
  • [4] S.K. Kulkarni, B. George, and R. Mathur, Phytother. Res., 12 , 451 (1998)
  • [5] J.N. Dhuley, Phytother. Res., 15 , 311 (2001)
  • [6] A.D. Kinghorn, B.N. Su, D.S. Jang, L.C. Chang, D. Lee, J.Q. Gu, E.J. Carcache-Blanco, A.C. Pawlus, S.K. Lee, E.J. Park, M. Cuedei, J.J. Gills, K. Bhat, H.S. Park, E. Mata-Greenwod, L.L. Song, M. Jang, and J.M. Pessuto, Planta Med., 70 , 691 (2004)
  • [7] C. Tohda, K. Komaatuse, and T. Kuboyama, J. Tradit. Med., 22 , 176 2005
  • [8] H. Ichikawa, Y. Takada, S. Shishodia, B. Jayaprakasam, M.G. Nair, and B.B. Aggrawal, Mol. Cancer Ther., 5 , 1434 (2006)
  • [9] M. Kaileh, W.V. Berghe, A. Heyerick, J. Horion, J. Plette, C. Libert, D. De Keukelerie, T. Essawi, and G. Haegeman, J. Biol. Chem., 282 , 4253 (2007)
  • [10] R.S. Sangwan, N.D. Chaurasiya, L.N. Misra, P. Lal, G.C. Uniyal, N.S. Sangwan, A.K. Srivastava, K.A. Suri, G.N. Qazi, and R. Tuli, US Patent # 7, 108, 870 (2005)
  • [11] N.D. Chaurasiya, G.C. Uniyal, P. Lal, L. Misra, N.S. Sangwan, R. Tuli, R.S. Sangwa, Phytochem. Anal., 19 , 148 (2008)
  • [12] S. Dalavayi, S.M. Kulkarni, R.L. Itikala, and S. Itikala, Ind. J. Pharm. Sci., 68 , 253 (2006)
  • [13] M. Ganzera, M.I. Choudhary, and I.A. Khan, Fitoterapia, 74 , 68 (2003)
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-9abcf14c-2b4a-4582-a80b-4e663bcfb358
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