Probabilistic study of bone remodeling using finite element analysis

• Autorzy: Werner C. , Gorla R. S. R.

Identyfikatory

DOI

10.2478/ijame-2013-0055

• Języki publikacji: EN

Abstrakty

EN

The dynamic bone remodeling process is a computationally challenging research area that struggles to understand the actual mechanisms. It has been observed that a mechanical stimulus in the bone greatly affects the remodeling process. A 3D finite element model of a femur is created and a probabilistic analysis is performed on the model. The probabilistic analysis measures the sensitivities of various parameters related to the material properties, geometric properties, and the three load cases defined as Single Leg Stance, Abduction, and Adduction. The sensitivity of each parameter is based on the calculated maximum mechanical stimulus and analyzed at various values of probabilities ranging from 0.001 to 0.999. The analysis showed that the parameters associated with the Single Leg Stance load case had the highest sensitivity with a probability of 0.99 and the angle of the force applied to the joint of the proximal femur had the overall highest sensitivity.

Słowa kluczowe

EN

probabilistic analysis; bone remodeling; finite element analysis

PL

analiza probabilistyczna; przebudowa kości; analiza elementów skończonych

• Wydawca: Oficyna Wydawnicza Uniwersytetu Zielonogórskiego
• Czasopismo: International Journal of Applied Mechanics and Engineering
• Rocznik: 2013
• Tom: Vol. 18, no. 3
• Strony: 911--921
• Opis fizyczny: Bibliogr. 2 poz., rys., tab., wykr.

Twórcy

autor

Werner C.

• Department of Mechanical Engineering Cleveland State University Cleveland, Ohio 44115 USA

autor

Gorla R. S. R.

• Department of Mechanical Engineering Cleveland State University Cleveland, Ohio 44115 USA

Bibliografia

• Hazelwood S.J., Martin R.B., Rashid M.M. and Rodrigo J.J. (2001): A mechanistic model for internal bone remodeling exhibits different dynamic responses in disuse and overload. – Journal of Biomechanics, vol.34(3), pp.299-308.
• Hazelwood S.J. and Castillo A.B. (2007): Simulated effects of marathon training on bone density, remodeling, and microdamage accumulation of the femur. – International Journal of Fatigue, vol.29, pp.1057-1064.