DNA Ion Detector and Logic Circulation Amplification Model Based on Mercury and Silver Ions

• Autorzy: Guo Bingjie , Wang Luhui , Wu Tao , Dong Yafei

Identyfikatory

DOI

10.3233/FI-2019-1762

• Języki publikacji: EN

Abstrakty

EN

Here, two two-way ion detector (TWID) and one DNA cascade logic circuit and signal amplifier model had been created. Firstly, we have constructed two bidirectional mercury and silver ion detectors, both of which can be used to detect mercury and silver ions at the same time, that means a single molecule can detect two kinds of heavy metal ions at the same time. The unique design of the switches offers significant advantages over existing methods. In addition, the two bidirectional ion detectors enable the design of the logic gates (OR, AND) using Ag⁺ and Hg²⁺ as inputs. Secondly, we constructed a two-level “AND” logic gate by combining the above two logic gates. This logic model takes the output of “OR” logic gate as the input of the next logic gate, which not only realizes the logic operation, but also achieves the function of signal amplification. We are able to recognize the logic output signals effortlessly by observing the amount of fluorescence. It’s a simple, economic and safe approach for the design of a complex multiple-input DNA logic circulation amplification model. Finally, we proved the feasibility of our model by PAGE and fluorescence alteration.

Słowa kluczowe

EN

detect; DNA computing; ions-medicated; logic gate

• Wydawca: IOS Press
• Czasopismo: Fundamenta Informaticae
• Rocznik: 2019
• Tom: Vol. 164, nr 2-3
• Strony: 195--205
• Opis fizyczny: Bibliogr. 38 poz., rys., tab., wykr.

Twórcy

autor

Guo Bingjie

• Department of Life Science, Shaanxi Normal University, Xi’an 710119, China

autor

Wang Luhui

• Department of Life Science, Shaanxi Normal University, Xi’an 710119, China

autor

Wu Tao

• Department of Life Science, Shaanxi Normal University, Xi’an 710119, China

autor

Dong Yafei

• Department of Life Science & National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, Shaanxi Normal University, Xi’an 710119, China

Bibliografia

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Uwagi

Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2019).