Quantitative and dosimetric analysis for treating synchronous bilateral breast cancer using two radiotherapy planning techniques

• Autorzy: Mermut Özlem , Ata Aysun Ozsoy , Can Trabulus Didem

Identyfikatory

DOI

10.2478/pjmpe-2021-0024

• Języki publikacji: EN

Abstrakty

EN

Objective: We compared mono-isocenter and dual-isocenter plans in synchronous bilateral breast cancer (SBBC), which is defined as tumours occurring simultaneously in both breasts, and evaluated the effects of these differences in plans on organs-at-risk (OARs). Materials and methods: We evaluated 10 women with early stage, nod negative (Tis-2N0M0) SBBC. The treatment dose was determined to be 50 Gy. We used mean dose and VXGy to evaluate the OARs. To evaluate the effectiveness of treatment plans, Homogeneity index (HI), conformity index (CI) and sigma index (SI) and monitor units (MU) of monoisocenter (MIT) and dual-isocenter (DIT) plans were compared. During bilateral breast planning, for the single-centre plan, the isocenter was placed at the center of both breasts at a depth of 3-4 cm. For the two-center plan, dual-isocenters were placed on the right and left breasts. Results: No significant difference between the techniques in terms of the scope of the target volume was observed. Statistically significant results were not achieved in MIT and DIT plans for OARs. Upon comparing MIT and DIT, the right-side monitor unit (MU) value in DIT (p = 0.011) was statistically significantly lower than that in MIT. Upon comparing right-left side MIT and DIT, the MU value (p = 0.028) was significantly lower in DIT than MIT. Conclusion: SBBC irradiation is more complex than unilateral breast radiotherapy. No significant difference between both techniques and OARs was observed. However, we recommend MIT as a priority technique due to the ability to protect OARs, ease of administration during treatment, and the fact that the patient stays in the treatment unit for a shorter period of time.

Słowa kluczowe

EN

dosimetric comparison; mono-isocenter; dual-isocenter; synchronous bilateral breast cancer

• Wydawca: Polskie Towarzystwo Fizyki Medycznej ; De Gruyter
• Czasopismo: Polish Journal of Medical Physics and Engineering
• Rocznik: 2021
• Tom: Vol. 27, Iss. 3
• Strony: 201--206
• Opis fizyczny: Bibliogr. 23 poz., rys., tab.

Twórcy

autor

Mermut Özlem

• Department of Radiation Oncology, University of Health Sciences Istanbul Training and Research Hospital, Turkey

autor

Ata Aysun Ozsoy

• Department of Radiation Oncology, MNT Health Services Medical Physicist, University of Health Sciences Istanbul Training and Research Hospital, Turkey

autor

Can Trabulus Didem

• Clinic of General Surgery, University of Health Sciences Istanbul Training and Research Hospital, Turkey

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).