Synthesis of bees’ chitosan based hydrogels containing Aloe vera

• Autorzy: Kudłacik-Kramarczyk S. , Drabczyk A. , Tyliszczak B.

Identyfikatory

DOI

10.14597/infraeco.2017.4.2.127

• Języki publikacji: EN

Abstrakty

EN

Chitosan based hydrogels due to their specific properties and structure belong to the group of materials widely used in medicine. They are used as drug carriers with controlled release of active substances and in the preparation of innovative wound dressings. The main aim of the conducted research was the choice of the most favorable parameters for carrying the cross-linking reaction by means of UV radiation and microwaves. Subsequently, an adequate composition of the mixture containing chitosan and gelatin for further modification of such prepared the polymer matrix with Aloe vera extract was selected. Subsequently, an impact of introduction of Aloe vera extract into hydrogel on its physicochemical properties and structure was determined. The scope of the research included the measurement of swelling abilities of hydrogels in distilled water and selected simulated body fluids as well as incubation studies aimed at determination of tendency of prepared materials to degradation in previously mentioned fluids and their compatibility in relation to such environments. In order to characterize the chemical structure of the polymers and impact of incubation on this structure spectroscopic analysis was performed. Microscopic analysis was used to define the surface morphology of the hydrogels. Moreover, materials containing Aloe vera extract were subjected to the studies of release of additive from hydrogel matrix. Research was conducted both in acid and alkaline environment.

Słowa kluczowe

EN

beetosan; chitosan; hydrogels; Aloe vera; bees; waste management

• Wydawca: Stowarzyszenie Infrastruktura i Ekologia Terenów Wiejskich
• Czasopismo: Infrastruktura i Ekologia Terenów Wiejskich
• Rocznik: 2017
• Tom: nr IV/2
• Strony: 1687--1698
• Opis fizyczny: Bibliogr. 13 poz., rys., tab., wykr.

Twórcy

autor

Kudłacik-Kramarczyk S.

• Institute of Inorganic Chemistry and Technology, Warszawska 24 St. 31-155 Cracow, Ph: 628-27-23

autor

Drabczyk A.

• Institute of Inorganic Chemistry and Technology, Warszawska 24 St. 31-155 Cracow, Ph: 628-27-23

autor

Tyliszczak B.

• Department of Chemistry and Technology of Polymers, Warszawska 24 St. 31-155 Cracow, Ph: 628-25-72

Bibliografia

• Anjum S., Arora A., Alam M.S., Gupta B. (2016). Development of antimicrobial and scar preventive chitosan hydrogel wound dressings. International Journal of Pharmaceutics. 508, 92-101.
• Baruah A., Bordoloi M., Baruah H.P.D. (2016). Aloe vera: A multipurpose industrial crop. Industrial Crops and Products. 94, 951-963.
• Bhattarai N., Gunn J., Zhang M. (2010). Chitosan-based hydrogels for controlled, localized drug delivery. Advanced Drug Delivery Reviews. 62, 83-99.
• Cieślik E., Turcza K. (2015). Właściwości prozdrowotne aloesu zwyczajnego Aloe vera (L.) Webb. (Aloe barbadensis Mill.). Postępy Fitoterapii 16, 117-124.
• Guiseppi-Elie A. (2010). Electroconductive hydrogels: Synthesis, characterization and biomedical applications. Biomaterials. 31, 2701-2716.
• Kirschner C.M., Anseth K.S. (2013). Hydrogels in healthcare: From static to dynamic material microenvironment. Acta Materialia. 61, 931-944.
• Patrulea V., Ostafe V., Borchard G., Jordan O. (2015). Chitosan as a starting material for wound healing applications. European Journal of Pharmaceutics and Biopharmaceutics. 97, 417-426.
• Radha M.H., Laxmipriya N.P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine. 5, 21-26.
• Rajeswari R., Umadevi M., Pushpa R., Selvavenkadesh S. (2004). Aloe vera: The Miracle Plant Its Medicinal and Traditional Uses in India. Journal of Pharmacognosy and Photochemistry. 1, 118-124.
• Sanchez-Machado D.I., Lopez-Cervantez J., Sendon R., Sanches-Silva A. (2017). Aloe vera: Ancient knowledge with new frontiers. Trends in Food Science & Technology. 61, 94-102.
• Sepantafar M., Maheronnaghsh R., Mohammadi H., Radmanesh F., Hasani-sadrabadi M.M., Ebrahimi M., Baharvand H. (2017). Engineered Hydrogels in Cancer Therapy and Diagnosis. Trends in Biotechnology. 35(11), 1074-1087.
• Silverstein R.M. (2015). Spectrometric identification of organic compounds, John Wiley & Sons.
• Witthayaprapakorn C. (2011). Design and Preparation of Synthetic Hydrogels Via Photopolymerization for Biomedical Use as Wound Dressings. Procedia Engineering. 8, 286-291.

Uwagi

Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2018).