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Funkcjonalizacja chitozanem i miodem włókniny wiskozowej do zastosowań medycznych
Języki publikacji
Abstrakty
The aim of this research was to develop the formulation of chitosan in combination with honey in different mass proportions of each of the components within the separate mixture. Such a formulation could serve as a functional coating suitable for wound healing. From the perspective of different formulations used within research presented, it is assumed that the different mass fraction of components will affect antimicrobial and antioxidant activity of the functionalised substrate differently. To apply the separate formulation onto a non-woven viscose substrate, the conventional pad-drying process was selected. Moreover a study of the effectiveness of the individual treatment was performed systematically, which is also reflected in the systematics of the experimental techniques selected. Considering antioxidant and antimicrobial action, honey-functionalised non-woven viscose shows higher effectiveness if compared to non-woven viscose functionalized with the chitosan:honey combination.
Celem pracy było opracowanie z kombinacji chitozanu i miodu preparatu służącego jako przyspieszająca gojenie ran powłoka włóknin wiskozowych. W prezentowanych badaniach założono, że różna frakcja masowa składników wpływa odmiennie na działanie przeciwdrobnoustrojowe i przeciwutleniające funkcjonalizowanego podłoża. W celu zastosowania oddzielnego preparatu na nietkanym podłożu wiskozy, wybrano konwencjonalny proces osuszania. Biorąc pod uwagę działanie przeciwutleniające i przeciwbakteryjne, włóknina funkcjonalizowana miodem wykazywała większą skuteczność w porównaniu z włókniną wiskozową funkcjonalizowaną kombinacją chitozanu i miodu.
Czasopismo
Rocznik
Strony
67--72
Opis fizyczny
Bibliogr. 16 poz., rys., tab.
Twórcy
autor
- University of Maribor, Faculty of Mechanical Engineering, Institute of Engineering Materials and Design, Smetanova ulica 17, 2000 Maribor, Slovenia
autor
- Tosama d.o.o.; Vir, Šaranovičeva c. 35; 1230 Domžale, Slovenia
autor
- University of Maribor, Faculty of Mechanical Engineering, Institute of Engineering Materials and Design, Smetanova ulica 17, 2000 Maribor, Slovenia
autor
- University of Maribor, Faculty of Mechanical Engineering, Institute of Engineering Materials and Design, Smetanova ulica 17, 2000 Maribor, Slovenia
autor
- University of Maribor, Faculty of Mechanical Engineering, Institute of Engineering Materials and Design, Smetanova ulica 17, 2000 Maribor, Slovenia
Bibliografia
- 1. Šauperl O, Tompa J, Volmajer Valh J. Influence of the temperature on the efficiency of cellulose treatment using copolymer chitosan-eugenol. J. Eng. Fibers Fabr. 2014; 9: 107-114.
- 2. Han JW, Jeong JK, Gurunathan S, Choi YJ, Das J, Kwon DN, Cho SG, Park C, Seo HG, Park JK, Kim JH. Male- and female-derived somatic and germ cell-specific toxicity of silver nanoparticles in mouse. Nanotoxicology 2016; 10: 361-373.
- 3. Fras Zemljič L, Kosalec I, Munda M, Strnad S, Kolar M, Bračič M, Šauperl O. Antimicrobial efficiency evaluation by monitoring potassium efflux for cellulose fibres functionalised by chitosan. Cellulose 2015; Online First Apr: 1-10.
- 4. Swidwinska-Gajewska AM, Czerczak S. Nanosilver. Med Pr 2014; 65(6):831–845.
- 5. Kumar R, Muzzarelli RAA, Muzzareli C, Domb AJ. Chitosan chemistry and pharmaceutical perspectives. Chemicals Reviews 2004; 104: 6043-6045.
- 6. Ristić T, Fras Zemljič L, Novak M, Kralj Kunčič M, Sonjak S, Gunde Cimerman N, Strnad S. »Antimicrobial efficiency of functionalized cellulose fibres as potential medical textiles”, Science against microbial pathogens: communicating current research and technological advances. Formatex 2011; 36-51.
- 7. Chandan KS, Khanna S, Gordillo G, Bagchi D, Bagchi M, Sashwati R. Oxygen, Oxidants, and Antioxidants in Wound Healing, An Emerging Paradigm. Ann. N.Y. Acad. SCi. 2002; 957: 239-249.
- 8. Christian L. Baum MD, Christopher J, Arpey MD. Normal Cutaneous Wound Healing: Clinical Correlation with Cellular and Molecular Events. Dermatol. Surg. 2005; 31(6): 674–686.
- 9. Masek A, Chrzescijanska E, Latos M, Zaborski M. Influence of hydroxyl substitution on flavanone antioxidants. Food Chem. 2016; 215: 501-507.
- 10. Dudonné S, Vitrac X, Coutière P, Woillez M, Mérillon JM. Comparative study of antioxidant properties and total phenolic content of 30 plant extracts of industrial interest using DPPH, ABTS, FRAP, SOD, and ORAC assays. J. Agric. Food Chem. 2009; 57(5):1768–1774.
- 11. Čakara D, Fras Zemljič L, Bračič M, Stana-Kleinschek K. Protonation behavior of cotton fabric with irreversibly adsorbed chitosan: a potentiometric titration study. Carbohydr. Polym. 2009; 78(1): 36-40.
- 12. Šauperl O, Volmajer Valh J. Viscose functionalisation with a combination of chitosan/BTCA using microwaves. Fibres Text. East. Eur. 2013; 5(101): 24-29.
- 13. Bang LM, Buntting C, Molan P. The Effect of Dilution on the Rate of Hydrogen Peroxide Production in Honey and Its Implications for Wound Healing. The journal of alternative and complementary medicine 2002; 9(2): 267–273.
- 14. Kwakman PHS, te Velde AA, de Boer L, Speijer D, Vandenbroucke-Grauls CMJE, Zaat SAJ, How honey kills bacteria. The FASEB Journal 2010; 24(7): 2576–2582.
- 15. Sackett WG. Honey as a carrier of intestinal diseases, Bull Colorado State Univ Agric Exp Stn 1919; 252: 1-18.
- 16. White JW, Subers MH, Schepartz AI. The identification of inhibine, the antibacterial factor in honey, as hydrogen peroxide and its origin in a honey glucose-oxidase system. Biochim Biophys Acta 1963; 73: 57-70.
Typ dokumentu
Bibliografia
Identyfikator YADDA
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