In silico analysis of methylation of the selected genes using computer programs based on various analytical techniques

• Autorzy: Gryzińska M. , Jakubczak A. , Stryjecki R. , Jeżewska-Witkowska G.

Identyfikatory

DOI

10.1016/j.bbe.2014.09.002

• Języki publikacji: EN

Abstrakty

EN

Selected genes were analyzed in silico in three species: red fox (Vulpes vulpes), raccoon dog (Nyctereutes procyonoides), and dog (Canis lupus familiaris). This type of analysis exemplifies current and potential research on gene expression. Four nucleotide sequences, of the genes IGF1, MYO15A, PAX3 and MC1R, were obtained from the NCBI online database. The analyses focused on the presence of CpG islands and two analytical techniques, BSP and MSP. The results from three computer programs, CpG Island Searcher^®, BiSearch^® and MethPrimer^®, were discussed in detail. The applications were compared in terms of their functionality and usefulness.

Słowa kluczowe

EN

bioinformatics; DNA methylation; epigenetics; in silico; MSP; BSP

PL

bioinformatyka; metylacja DNA; epigenetyka

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2015
• Tom: Vol. 35, no. 3
• Strony: 169--175
• Opis fizyczny: Bibliogr. 34 poz., tab., wykr.

Twórcy

autor

Gryzińska M.

• Department of Biological Basis of Animal Production, Faculty of Biology and Animal Breeding, University of Life Sciences in Lublin, Poland

autor

Jakubczak A.

• Department of Biological Basis of Animal Production, Faculty of Biology and Animal Breeding, University of Life Sciences in Lublin, Poland

autor

Stryjecki R.

• Department of Zoology, Ecology and Wildlife Management, University of Life Sciences in Lublin, ul. Akademicka 13, 20-950 Lublin, Poland

autor

Jeżewska-Witkowska G.

• Department of Biological Basis of Animal Production, Faculty of Biology and Animal Breeding, University of Life Sciences in Lublin, Poland

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