Synthesis and Antimicrobial Screening of 2"-amino-4"-[2-(4'-chlorophenyl) -6-methyl imidazo[1, 2-a]pyridine -3-yl]-6"-aryl-4"-H-pyran-3"- Carbonitrile

• Autorzy: Bhuva V. V. , Bhadani V. N. , Purohit H. D. , Purohit D. M.

Identyfikatory

DOI

10.18052/www.scipress.com/ILCPA.49.149

• Języki publikacji: EN

Abstrakty

EN

3-Cyano-4,6-disubstituted 4H-pyrans are endowed with a variety of pharmacodynamic activities Looking to the interesting properties of cyanopyrans, it was considered worthwhile to synthesis some new 2"-amino-4"-[2-(4'-chlorophenyl) -6-methyl imidazo [1,2-a] pyridin-3-yl]-6"-aryl-4"-H-pyran-3"- carbonitrile ( 4a-4l ) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50μg/mL. The structures of the products have been elucidated by IR, 1H-NMR, Mass spectral data, elemental analysis and thin layer chromatography.

Słowa kluczowe

EN

antibacterial activity; antifungal activity; Cyanopyrans

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2015
• Tom: Vol. 49
• Strony: 149--154
• Opis fizyczny: Bibliogr. 16 poz., rys., tab., wz.

Twórcy

autor

Bhuva V. V.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India

autor

Bhadani V. N.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India

autor

Purohit H. D.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India

autor

Purohit D. M.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India

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