Synthesis and characterization of fully substituted pyrimidines by using ketene dithioacetal as potent antimicrobial agent

• Autorzy: Khunt H. R. , Pipaliya P. P. , Ghelani S. M. , Babariya J. S. , Naliapara Y. T.
• Języki publikacji: EN

Abstrakty

EN

Various ketene dithioacetals of acetoacetanilides were reacted with guanidine nitrate in the presence of base to produce the 2-amino-4-isopropyl-6-alkoxy-N-arylpyrimidine-5-carboxamide derivatives with good yields. All the synthesized compounds were characterized by mass, NMR and IR and also evaluated for antimicrobial activity against five different bacterial and fungal strains. The compounds 4i, 4k and 4l has found comparatively good active against all the bacterial strains.

Słowa kluczowe

EN

ketene dithioacetal; pyrimidines; guanidine; biginelli reaction

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2014
• Tom: Vol. 5
• Strony: 134--141
• Opis fizyczny: Bibliogr. 12 poz., tab., wz.

Twórcy

autor

Khunt H. R.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Pipaliya P. P.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Ghelani S. M.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Babariya J. S.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

autor

Naliapara Y. T.

• Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

Bibliografia

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