Antibacterial Composite Layers on Ti: Role of ZnO Nanoparticles

• Autorzy: Roguska A. , Belcarz A. , Suchecki P. , Andrzejczuk M. , Lewandowska M.

Identyfikatory

DOI

10.1515/amm-2016-0039

• Języki publikacji: EN

Abstrakty

EN

Problem of Post-operative infections of implant materials caused by bacterial adhesion to their surfaces is very serious. Enhancement of antibacterial properties is potentially beneficial for biomaterials value. Therefore, the metallic and metallic oxide nanoparticles attract particular attention as antimicrobial factors. The aim of this work was to create nanotubular (NT) oxide layers on Ti with the addition of ZnO nanoparticles, designed for antibacterial biomedical coatings. Antimicrobial activities of titanium, TiO₂ NT and ZnO/TiO₂ NT surfaces were evaluated against bacterial strain typical for orthopaedic infections: S. epidermidis. TiO₂ NT alone killed the free bacterial cells significantly but promoted their adhesion to the surfaces. The presence of moderate amount of ZnO nanoparticles significantly reduced the S. epidermidis cells adhesion and viability of bacterial cells in contact with modified surfaces. However, higher amount of loaded nanoZnO showed the reduced antimicrobial properties than the medium amount, suggesting the overdose effect.

Słowa kluczowe

EN

bone implants; TiO2 nanotubes; ZnO nanoparticles; Staphylococcus epidermidis; antibacterial properties

• Wydawca: Institute of Metallurgy and Materials Science of Polish Academy of Sciences ; Committee of Materials Engineering and Metallurgy of Polish Academy of Sciences
• Czasopismo: Archives of Metallurgy and Materials
• Rocznik: 2016
• Tom: Vol. 61, iss. 1
• Strony: 213--216
• Opis fizyczny: Bibliogr. 15 poz., rys., tab.

Twórcy

autor

Roguska A.

• Institute of Physical Chemistry, Polish Academy of Sciences, Warszawa , Poland

autor

Belcarz A.

• Chair and Department of Biochemistry and Biotechnology, Medical University of Lublin, Lublin, Poland

autor

Suchecki P.

• Faculty of Material Science and Engineering, Warsaw University of Technology, Warszawa, Poland

autor

Andrzejczuk M.

• Faculty of Material Science and Engineering, Warsaw University of Technology, Warszawa, Poland

autor

Lewandowska M.

• Faculty of Material Science and Engineering, Warsaw University of Technology, Warszawa, Poland

Bibliografia

• [1] A. G. Gristina,Clin.Orthop.Relat. R 298,106 (1994).
• [2] A. D. Hanssen, J. A. Rand, J. Bone Joint Surg. 80A,910 (1998).
• [3] M. Sygnatowicz, K. Keyshar, A. Tiwari, JOM 62, 65 (2010).
• [4] C. K. Popat, M. Eltgroth, J. T. La Tempa, A. C. Grimes,A. T. Desai, Biomaterials 28, 4880 (2007).
• [5] P. H. Chua, K. G. Neoh, E. T. Kang, W. Wang, Biomaterials 29, 1412 (2008).
• [6] Y. Z. Wan, G. Y. Xiong, H. Liang, S. Raman, F. He, Y. Huang, Appl. Surf. Sci.253, 9426 (2007).
• [7] J. Xu, G. Ding, J. Li, S. Yang, B. Fang, H. Sun, Y. Zhou, Apll. Surf. Sci. 256, 7540 (2010).
• [8] A. J. Huh, Y. J. Kwon, J. Control. Release 156, 128 (2011).
• [9] E. Weir, A. Lawlor, A. Whelan, F. Regan, Analyst 133, 835 (2008).
• [10] M. Rai, A. Yadav, A. Gade,VTT SYMP27, 76 (2009).
• [11] M. Premanathan, K. Karthikeyan, K. Jeyasubramanian, G. Manivannan,Nanomed.-Nanotechnol. 7, 184 (2011).
• [12] G. Jin, H. Cao, Y. Qiao, F. Meng, H. Zhu, X. Liu, Colloid Surface B. 117, 158 (2014).
• [13] JIS Z 2801:2000. Antimicrobial products - test for antimicrobial activity and efficacy. Japanese Industrial Standard, Japanese Standard Association.
• [14] S. Nair, A. Sasidharan, R. V. Divya, D. Menon, K. Manzoor, S. Raina, J. Mater. Sci.-Mater. M.20, 253 (2009).
• [15] R. Brayner, R. Ferrari-Illiou, N. Brivois, S. Djediat, M. Benedetti, F. Fiévet, NanoLett.6, 866 (2006).

Uwagi

PL

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę